GSE120014[Accession] - GEO DataSets - NCBI

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Items: 10

Select item 2001200141.

The Hippo Pathway Prevents YAP/TAZ–Driven Hypertranscription and Controls Neural Progenitor Number [ChIP-seq]

(Submitter supplied) The Hippo pathway controls the activity of YAP/TAZ transcriptional coactivators through a kinase cascade. Despite the critical role of this pathway in tissue growth and tumorigenesis, it is not fully understood how YAP/TAZ–mediated transcription drives proliferation. By analyzing the effects of inactivating LATS1/2 kinases, the direct upstream inhibitors of YAP/TAZ, on mouse brain development and applying cell-number–normalized transcriptome analysis, we discovered that YAP/TAZ activation causes a global increase in transcription activity, known as hypertranscription, and upregulates many genes associated with increased biosynthetic capacity and proliferation. more...

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL17021
8 Samples

Download data: BED, BW

Series

Accession:: GSE120014

ID:: 200120014

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 1000170212.

Illumina HiSeq 2500 (Mus musculus)

Organism:: Mus musculus

10765 Series
293516 Samples

Platform

Accession:: GPL17021

ID:: 100017021

Select item 3033917153.

INPUT_ChIPSeq_dKO_rep2

Organism:: Mus musculus

Source name:: INPUT_ChIPSeq_dKO

Platform:: GPL17021
Series:: GSE120014 GSE120016

Download data: BW

Sample

Accession:: GSM3391715

ID:: 303391715

SRA Run Selector

Select item 3033917144.

INPUT_ChIPSeq_dKO_rep1

Organism:: Mus musculus

Source name:: INPUT_ChIPSeq_dKO

Platform:: GPL17021
Series:: GSE120014 GSE120016

Download data: BW

Sample

Accession:: GSM3391714

ID:: 303391714

SRA Run Selector

Select item 3033917135.

INPUT_ChIPSeq_WT_rep2

Organism:: Mus musculus

Source name:: INPUT_ChIPSeq_WT

Platform:: GPL17021
Series:: GSE120014 GSE120016

Download data: BW

Sample

Accession:: GSM3391713

ID:: 303391713

SRA Run Selector

Select item 3033917126.

INPUT_ChIPSeq_WT_rep1

Organism:: Mus musculus

Source name:: INPUT_ChIPSeq_WT

Platform:: GPL17021
Series:: GSE120014 GSE120016

Download data: BW

Sample

Accession:: GSM3391712

ID:: 303391712

SRA Run Selector

Select item 3033917117.

H3K4me3_ChIPSeq_dKO_rep2

Organism:: Mus musculus

Source name:: H3K4me3_ChIPSeq_dKO

Platform:: GPL17021
Series:: GSE120014 GSE120016

Download data: BED

Sample

Accession:: GSM3391711

ID:: 303391711

SRA Run Selector

Select item 3033917108.

H3K4me3_ChIPSeq_dKO_rep1

Organism:: Mus musculus

Source name:: H3K4me3_ChIPSeq_dKO

Platform:: GPL17021
Series:: GSE120014 GSE120016

Download data: BED

Sample

Accession:: GSM3391710

ID:: 303391710

SRA Run Selector

Select item 3033917099.

H3K4me3_ChIPSeq_WT_rep2

Organism:: Mus musculus

Source name:: H3K4me3_ChIPSeq_WT

Platform:: GPL17021
Series:: GSE120014 GSE120016

Download data: BED

Sample

Accession:: GSM3391709

ID:: 303391709

SRA Run Selector

Select item 30339170810.

H3K4me3_ChIPSeq_WT_rep1

Organism:: Mus musculus

Source name:: H3K4me3_ChIPSeq_WT

Platform:: GPL17021
Series:: GSE120014 GSE120016

Download data: BED

Sample

Accession:: GSM3391708

ID:: 303391708

SRA Run Selector

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GSE120014[Accession] (10)
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