GSE120015[Accession] - GEO DataSets - NCBI

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Items: 11

Select item 2001200151.

The Hippo Pathway Prevents YAP/TAZ–Driven Hypertranscription and Controls Neural Progenitor Number [RNA-seq]

(Submitter supplied) The Hippo pathway controls the activity of YAP/TAZ transcriptional coactivators through a kinase cascade. Despite the critical role of this pathway in tissue growth and tumorigenesis, it is not fully understood how YAP/TAZ–mediated transcription drives proliferation. By analyzing the effects of inactivating LATS1/2 kinases, the direct upstream inhibitors of YAP/TAZ, on mouse brain development and applying cell-number–normalized transcriptome analysis, we discovered that YAP/TAZ activation causes a global increase in transcription activity, known as hypertranscription, and upregulates many genes associated with increased biosynthetic capacity and proliferation. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL21103
9 Samples

Download data: TXT

Series

Accession:: GSE120015

ID:: 200120015

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 1000211032.

Illumina HiSeq 4000 (Mus musculus)

Organism:: Mus musculus

6342 Series
138248 Samples

Platform

Accession:: GPL21103

ID:: 100021103

Select item 3033917243.

Organism:: Mus musculus

Source name:: dKO_telencephalons

Platform:: GPL21103
Series:: GSE120015 GSE120016

Download data: TXT

Sample

Accession:: GSM3391724

ID:: 303391724

SRA Run Selector

Select item 3033917234.

Organism:: Mus musculus

Source name:: dKO_telencephalons

Platform:: GPL21103
Series:: GSE120015 GSE120016

Download data: TXT

Sample

Accession:: GSM3391723

ID:: 303391723

SRA Run Selector

Select item 3033917225.

Organism:: Mus musculus

Source name:: dKO_telencephalons

Platform:: GPL21103
Series:: GSE120015 GSE120016

Download data: TXT

Sample

Accession:: GSM3391722

ID:: 303391722

SRA Run Selector

Select item 3033917216.

Organism:: Mus musculus

Source name:: dKO_telencephalons

Platform:: GPL21103
Series:: GSE120015 GSE120016

Download data: TXT

Sample

Accession:: GSM3391721

ID:: 303391721

SRA Run Selector

Select item 3033917207.

Organism:: Mus musculus

Source name:: WT_telencephalons

Platform:: GPL21103
Series:: GSE120015 GSE120016

Download data: TXT

Sample

Accession:: GSM3391720

ID:: 303391720

SRA Run Selector

Select item 3033917198.

Organism:: Mus musculus

Source name:: WT_telencephalons

Platform:: GPL21103
Series:: GSE120015 GSE120016

Download data: TXT

Sample

Accession:: GSM3391719

ID:: 303391719

SRA Run Selector

Select item 3033917189.

Organism:: Mus musculus

Source name:: WT_telencephalons

Platform:: GPL21103
Series:: GSE120015 GSE120016

Download data: TXT

Sample

Accession:: GSM3391718

ID:: 303391718

SRA Run Selector

Select item 30339171710.

Organism:: Mus musculus

Source name:: WT_telencephalons

Platform:: GPL21103
Series:: GSE120015 GSE120016

Download data: TXT

Sample

Accession:: GSM3391717

ID:: 303391717

SRA Run Selector

Select item 30339171611.

Organism:: Mus musculus

Source name:: WT_telencephalons

Platform:: GPL21103
Series:: GSE120015 GSE120016

Download data: TXT

Sample

Accession:: GSM3391716

ID:: 303391716

SRA Run Selector

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