GSE124224[Accession] - GEO DataSets - NCBI

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ARID1A is a critical regulator of luminal identity and therapeutic response in oestrogen receptor-positive breast cancer (ATAC-Seq)

(Submitter supplied) Mutations in ARID1A, a subunit of the SWI/SNF chromatin remodelling complex, are the most common somatic alteration of the SWI/SNF complex across all cancers including oestrogen receptor positive (ER)+ breast cancer. We have recently reported that ARID1A inactivating mutations are present at a high frequency in advanced endocrine resistant ER+ breast cancer. In parallel, to identify mechanisms of resistance to endocrine therapy in breast cancer, we performed an epigenome CRISPR/CAS9 knockout screen that identified ARID1A as the top candidate whose loss determines resistance to the ER degrader fulvestrant. more...

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL11154
20 Samples

Download data: BW

Series

Accession:: GSE124224

ID:: 200124224

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 1000111542.

Illumina HiSeq 2000 (Homo sapiens)

Organism:: Homo sapiens

10550 Series
183623 Samples

Platform

Accession:: GPL11154

ID:: 100011154

Select item 3035259953.

ATAC-Seq Sample_FULV_sg6_KO_2

Organism:: Homo sapiens

Source name:: Breast Cancer Cell

Platform:: GPL11154
Series:: GSE124224 GSE124228

Download data: BW

Sample

Accession:: GSM3525995

ID:: 303525995

SRA Run Selector

Select item 3035259944.

ATAC-Seq Sample_FULV_sg6_KO_1

Organism:: Homo sapiens

Source name:: Breast Cancer Cell

Platform:: GPL11154
Series:: GSE124224 GSE124228

Download data: BW

Sample

Accession:: GSM3525994

ID:: 303525994

SRA Run Selector

Select item 3035259935.

ATAC-Seq Sample_FULV_sg2_KO_2

Organism:: Homo sapiens

Source name:: Breast Cancer Cell

Platform:: GPL11154
Series:: GSE124224 GSE124228

Download data: BW

Sample

Accession:: GSM3525993

ID:: 303525993

SRA Run Selector

Select item 3035259926.

ATAC-Seq Sample_FULV_sg2_KO_1

Organism:: Homo sapiens

Source name:: Breast Cancer Cell

Platform:: GPL11154
Series:: GSE124224 GSE124228

Download data: BW

Sample

Accession:: GSM3525992

ID:: 303525992

SRA Run Selector

Select item 3035259917.

ATAC-Seq Sample_FULV_sg1_KO_2

Organism:: Homo sapiens

Source name:: Breast Cancer Cell

Platform:: GPL11154
Series:: GSE124224 GSE124228

Download data: BW

Sample

Accession:: GSM3525991

ID:: 303525991

SRA Run Selector

Select item 3035259908.

ATAC-Seq Sample_FULV_sg1_KO_1

Organism:: Homo sapiens

Source name:: Breast Cancer Cell

Platform:: GPL11154
Series:: GSE124224 GSE124228

Download data: BW

Sample

Accession:: GSM3525990

ID:: 303525990

SRA Run Selector

Select item 3035259899.

ATAC-Seq Sample_FULV_sg13_Control_2

Organism:: Homo sapiens

Source name:: Breast Cancer Cell

Platform:: GPL11154
Series:: GSE124224 GSE124228

Download data: BW

Sample

Accession:: GSM3525989

ID:: 303525989

SRA Run Selector

Select item 30352598810.

ATAC-Seq Sample_FULV_sg13_Control_1

Organism:: Homo sapiens

Source name:: Breast Cancer Cell

Platform:: GPL11154
Series:: GSE124224 GSE124228

Download data: BW

Sample

Accession:: GSM3525988

ID:: 303525988

SRA Run Selector

Select item 30352598711.

ATAC-Seq Sample_FULV_sg12_Control_2

Organism:: Homo sapiens

Source name:: Breast Cancer Cell

Platform:: GPL11154
Series:: GSE124224 GSE124228

Download data: BW

Sample

Accession:: GSM3525987

ID:: 303525987

SRA Run Selector

Select item 30352598612.

ATAC-Seq Sample_FULV_sg12_Control_1

Organism:: Homo sapiens

Source name:: Breast Cancer Cell

Platform:: GPL11154
Series:: GSE124224 GSE124228

Download data: BW

Sample

Accession:: GSM3525986

ID:: 303525986

SRA Run Selector

Select item 30352598513.

ATAC-Seq Sample_DMSO_sg6_KO_2

Organism:: Homo sapiens

Source name:: Breast Cancer Cell

Platform:: GPL11154
Series:: GSE124224 GSE124228

Download data: BW

Sample

Accession:: GSM3525985

ID:: 303525985

SRA Run Selector

Select item 30352598414.

ATAC-Seq Sample_DMSO_sg6_KO_1

Organism:: Homo sapiens

Source name:: Breast Cancer Cell

Platform:: GPL11154
Series:: GSE124224 GSE124228

Download data: BW

Sample

Accession:: GSM3525984

ID:: 303525984

SRA Run Selector

Select item 30352598315.

ATAC-Seq Sample_DMSO_sg2_KO_2

Organism:: Homo sapiens

Source name:: Breast Cancer Cell

Platform:: GPL11154
Series:: GSE124224 GSE124228

Download data: BW

Sample

Accession:: GSM3525983

ID:: 303525983

SRA Run Selector

Select item 30352598216.

ATAC-Seq Sample_DMSO_sg2_KO_1

Organism:: Homo sapiens

Source name:: Breast Cancer Cell

Platform:: GPL11154
Series:: GSE124224 GSE124228

Download data: BW

Sample

Accession:: GSM3525982

ID:: 303525982

SRA Run Selector

Select item 30352598117.

ATAC-Seq Sample_DMSO_sg1_KO_2

Organism:: Homo sapiens

Source name:: Breast Cancer Cell

Platform:: GPL11154
Series:: GSE124224 GSE124228

Download data: BW

Sample

Accession:: GSM3525981

ID:: 303525981

SRA Run Selector

Select item 30352598018.

ATAC-Seq Sample_DMSO_sg1_KO_1

Organism:: Homo sapiens

Source name:: Breast Cancer Cell

Platform:: GPL11154
Series:: GSE124224 GSE124228

Download data: BW

Sample

Accession:: GSM3525980

ID:: 303525980

SRA Run Selector

Select item 30352597919.

ATAC-Seq Sample_DMSO_sg13_Control_2

Organism:: Homo sapiens

Source name:: Breast Cancer Cell

Platform:: GPL11154
Series:: GSE124224 GSE124228

Download data: BW

Sample

Accession:: GSM3525979

ID:: 303525979

SRA Run Selector

Select item 30352597820.

ATAC-Seq Sample_DMSO_sg13_Control_1

Organism:: Homo sapiens

Source name:: Breast Cancer Cell

Platform:: GPL11154
Series:: GSE124224 GSE124228

Download data: BW

Sample

Accession:: GSM3525978

ID:: 303525978

SRA Run Selector

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GSE124224[Accession] (22)
GEO DataSets
MROH9[gene] (67)
ClinVar
maestro heat-like repeat-containing protein family member 9 isoform X3 [Homo sap...
maestro heat-like repeat-containing protein family member 9 isoform X3 [Homo sapiens]
gi|2462513848|ref|XP_054194833.1|

Protein
Wdr35 WD repeat domain 35 [Mus musculus]
Wdr35 WD repeat domain 35 [Mus musculus]
Gene ID:74682

Gene
74682[uid] AND (alive[prop]) (1)
Gene

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