GSE125618[Accession] - GEO DataSets - NCBI

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Select item 2001256181.

A Mediator-cohesin axis controls heterochromatin domain formation [RNA-seq]

(Submitter supplied) The genome consists of regions of transcriptionally active euchromatin and more silent heterochromatin. We reveal that the formation of heterochromatin domains requires cohesin turnover on DNA. Stabilization of cohesin on DNA through depletion of its release factor WAPL leads to a near-complete loss of heterochromatin domains. The Mediator CDK module controls heterochromatin in an opposing manner. Loss of this module leads to an almost binary partition of the genome into dense H3K9me3 domains, and regions devoid of H3K9me3 spanning the rest of the genome. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16791
35 Samples

Download data: TXT

Series

Accession:: GSE125618

ID:: 200125618

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 1000167912.

Illumina HiSeq 2500 (Homo sapiens)

Organism:: Homo sapiens

12192 Series
349329 Samples

Platform

Accession:: GPL16791

ID:: 100016791

Select item 3035789723.

MED12 rep 3C RNAseq

Organism:: Homo sapiens

Source name:: Hap1

Platform:: GPL16791
Series:: GSE125618 GSE125672

Download data: TXT

Sample

Accession:: GSM3578972

ID:: 303578972

SRA Run Selector

Select item 3035789714.

MED12 rep 3B RNAseq

Organism:: Homo sapiens

Source name:: Hap1

Platform:: GPL16791
Series:: GSE125618 GSE125672

Download data: TXT

Sample

Accession:: GSM3578971

ID:: 303578971

SRA Run Selector

Select item 3035789705.

MED12 rep 3A RNAseq

Organism:: Homo sapiens

Source name:: Hap1

Platform:: GPL16791
Series:: GSE125618 GSE125672

Download data: TXT

Sample

Accession:: GSM3578970

ID:: 303578970

SRA Run Selector

Select item 3035789696.

WAPL rep 3C RNAseq

Organism:: Homo sapiens

Source name:: Hap1

Platform:: GPL16791
Series:: GSE125618 GSE125672

Download data: TXT

Sample

Accession:: GSM3578969

ID:: 303578969

SRA Run Selector

Select item 3035789687.

WAPL rep 3B RNAseq

Organism:: Homo sapiens

Source name:: Hap1

Platform:: GPL16791
Series:: GSE125618 GSE125672

Download data: TXT

Sample

Accession:: GSM3578968

ID:: 303578968

SRA Run Selector

Select item 3035789678.

WAPL rep 3A RNAseq

Organism:: Homo sapiens

Source name:: Hap1

Platform:: GPL16791
Series:: GSE125618 GSE125672

Download data: TXT

Sample

Accession:: GSM3578967

ID:: 303578967

SRA Run Selector

Select item 3035789669.

WT rep 3C RNAseq

Organism:: Homo sapiens

Source name:: Hap1

Platform:: GPL16791
Series:: GSE125618 GSE125672

Download data: TXT

Sample

Accession:: GSM3578966

ID:: 303578966

SRA Run Selector

Select item 30357896510.

WT rep 3B RNAseq

Organism:: Homo sapiens

Source name:: Hap1

Platform:: GPL16791
Series:: GSE125618 GSE125672

Download data: TXT

Sample

Accession:: GSM3578965

ID:: 303578965

SRA Run Selector

Select item 30357896411.

WT rep 3A RNAseq

Organism:: Homo sapiens

Source name:: Hap1

Platform:: GPL16791
Series:: GSE125618 GSE125672

Download data: TXT

Sample

Accession:: GSM3578964

ID:: 303578964

SRA Run Selector

Select item 30357896312.

WAPL/MED12 rep 3C RNAseq

Organism:: Homo sapiens

Source name:: Hap1

Platform:: GPL16791
Series:: GSE125618 GSE125672

Download data: TXT

Sample

Accession:: GSM3578963

ID:: 303578963

SRA Run Selector

Select item 30357896213.

WAPL/MED12 rep 3B RNAseq

Organism:: Homo sapiens

Source name:: Hap1

Platform:: GPL16791
Series:: GSE125618 GSE125672

Download data: TXT

Sample

Accession:: GSM3578962

ID:: 303578962

SRA Run Selector

Select item 30357896114.

WAPL/MED12 rep 3A RNAseq

Organism:: Homo sapiens

Source name:: Hap1

Platform:: GPL16791
Series:: GSE125618 GSE125672

Download data: TXT

Sample

Accession:: GSM3578961

ID:: 303578961

SRA Run Selector

Select item 30357896015.

MED12 rep 2B RNAseq

Organism:: Homo sapiens

Source name:: Hap1

Platform:: GPL16791
Series:: GSE125618 GSE125672

Download data: TXT

Sample

Accession:: GSM3578960

ID:: 303578960

SRA Run Selector

Select item 30357895916.

WAPL rep 2B RNAseq

Organism:: Homo sapiens

Source name:: Hap1

Platform:: GPL16791
Series:: GSE125618 GSE125672

Download data: TXT

Sample

Accession:: GSM3578959

ID:: 303578959

SRA Run Selector

Select item 30357895817.

WT rep 2B RNAseq

Organism:: Homo sapiens

Source name:: Hap1

Platform:: GPL16791
Series:: GSE125618 GSE125672

Download data: TXT

Sample

Accession:: GSM3578958

ID:: 303578958

SRA Run Selector

Select item 30357895718.

WAPL/MED12 rep 2A RNAseq

Organism:: Homo sapiens

Source name:: Hap1

Platform:: GPL16791
Series:: GSE125618 GSE125672

Download data: TXT

Sample

Accession:: GSM3578957

ID:: 303578957

SRA Run Selector

Select item 30357895619.

MED12 rep 2A RNAseq

Organism:: Homo sapiens

Source name:: Hap1

Platform:: GPL16791
Series:: GSE125618 GSE125672

Download data: TXT

Sample

Accession:: GSM3578956

ID:: 303578956

SRA Run Selector

Select item 30357895520.

WAPL rep 2A RNAseq

Organism:: Homo sapiens

Source name:: Hap1

Platform:: GPL16791
Series:: GSE125618 GSE125672

Download data: TXT

Sample

Accession:: GSM3578955

ID:: 303578955

SRA Run Selector

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GSE125618[Accession] (37)
GEO DataSets
PREDICTED: Mus musculus predicted gene, 32650 (Gm32650), transcript variant X6, ...
PREDICTED: Mus musculus predicted gene, 32650 (Gm32650), transcript variant X6, ncRNA
gi|1720369227|ref|XR_880082.3|

Nucleotide
Unc5a unc-5 netrin receptor A [Rattus norvegicus]
Unc5a unc-5 netrin receptor A [Rattus norvegicus]
Gene ID:60629

Gene

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