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Items: 15

1.

Niche-Specific Re-Programming of Epigenetic Landscapes Drives Myeloid Cell Diversity in NASH [ATAC-seq]

(Submitter supplied) Tissue resident macrophages and recruited monocyte-derived macrophages contribute to host defense but also play pathological roles in a diverse range of human diseases. Multiple macrophage phenotypes are often represented in a diseased tissue, but we lack a deep understanding of the mechanisms that control diversification. Here we use a combination of genetic, genomic, and imaging approaches to investigate the origins and epigenetic trajectories of hepatic myeloid cells during a diet-induced model of nonalcoholic steatohepatitis (NASH). more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL19057 GPL21103
12 Samples
Download data: TXT
Series
Accession:
GSE128335
ID:
200128335
2.

Illumina HiSeq 4000 (Mus musculus)

Platform
Accession:
GPL21103
ID:
100021103
3.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
4.

ATAC_KN-RM_rep2

Organism:
Mus musculus
Source name:
Sorted hepatic macrophages
Platform:
GPL19057
Series:
GSE128335 GSE128338
Download data
Sample
Accession:
GSM4512325
ID:
304512325
5.

ATAC_KN-RM_rep1

Organism:
Mus musculus
Source name:
Sorted hepatic macrophages
Platform:
GPL19057
Series:
GSE128335 GSE128338
Download data
Sample
Accession:
GSM4512324
ID:
304512324
6.

ATAC_KC-N_rep1

Organism:
Mus musculus
Source name:
Sorted hepatic macrophages
Platform:
GPL19057
Series:
GSE128335 GSE128338
Download data
Sample
Accession:
GSM4512322
ID:
304512322
7.

ATAC_Ly6CLo-RM_rep2

Organism:
Mus musculus
Source name:
Sorted hepatic macrophages
Platform:
GPL21103
Series:
GSE128335 GSE128338
Download data
Sample
Accession:
GSM4512329
ID:
304512329
8.

ATAC_Ly6CLo-RM_rep1

Organism:
Mus musculus
Source name:
Sorted hepatic macrophages
Platform:
GPL21103
Series:
GSE128335 GSE128338
Download data
Sample
Accession:
GSM4512328
ID:
304512328
9.

ATAC_Ly6CHi-RM_rep2

Organism:
Mus musculus
Source name:
Sorted hepatic macrophages
Platform:
GPL21103
Series:
GSE128335 GSE128338
Download data
Sample
Accession:
GSM4512327
ID:
304512327
10.

ATAC_Ly6CHi-RM_rep1

Organism:
Mus musculus
Source name:
Sorted hepatic macrophages
Platform:
GPL21103
Series:
GSE128335 GSE128338
Download data
Sample
Accession:
GSM4512326
ID:
304512326
11.

ATAC_KC-N_rep2

Organism:
Mus musculus
Source name:
Sorted hepatic macrophages
Platform:
GPL21103
Series:
GSE128335 GSE128338
Download data
Sample
Accession:
GSM4512323
ID:
304512323
12.

ATAC_KC-H_rep2

Organism:
Mus musculus
Source name:
Sorted hepatic macrophages
Platform:
GPL21103
Series:
GSE128335 GSE128338
Download data
Sample
Accession:
GSM4512321
ID:
304512321
13.

ATAC_KC-H_rep1

Organism:
Mus musculus
Source name:
Sorted hepatic macrophages
Platform:
GPL21103
Series:
GSE128335 GSE128338
Download data
Sample
Accession:
GSM4512320
ID:
304512320
14.

ATAC_Blood-Ly6CHi-NASH_rep2

Organism:
Mus musculus
Source name:
Sorted peripheral monocytes
Platform:
GPL21103
Series:
GSE128335 GSE128338
Download data
Sample
Accession:
GSM4512319
ID:
304512319
15.

ATAC_Blood-Ly6CHi-NASH_rep1

Organism:
Mus musculus
Source name:
Sorted peripheral monocytes
Platform:
GPL21103
Series:
GSE128335 GSE128338
Download data
Sample
Accession:
GSM4512318
ID:
304512318
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Supplemental Content

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