GSE134388[Accession] - GEO DataSets - NCBI

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ALKBH5 regulates anti-PD-1 therapy response by modulating lactate and suppressive immune cell accumulation in tumor microenvironment

(Submitter supplied) We performed RNA-Seq and m6A RNA immunoprecipitation followed by high-throughput sequencing (MeRIP-Seq) to determine whether the altered gene expression and the regulatory functions in cancer immunotherapy could be a consequence of Alkbh5 or Fto-mediated m6A/m6Am demethylation. We used two m6A peak calling algorithms to find the common peaks between the two methods, and only kept the conserved peaks detected in all the biological replicates of each group to obtain the most stringent results. more...

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL21103 GPL20301
21 Samples

Download data: BB, MTX, TSV, TXT, XLSX

Series

Accession:: GSE134388

ID:: 200134388

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 1000211032.

Illumina HiSeq 4000 (Mus musculus)

Organism:: Mus musculus

6553 Series
140915 Samples

Platform

Accession:: GPL21103

ID:: 100021103

Select item 1000203013.

Illumina HiSeq 4000 (Homo sapiens)

Organism:: Homo sapiens

8440 Series
193105 Samples

Platform

Accession:: GPL20301

ID:: 100020301

Select item 3039456124.

B16F10-NTC cells implanted tumor-Mouse 2 [RNA-seq]

Organism:: Mus musculus

Source name:: B16F10-NTC cells implanted tumor-mouse

Platform:: GPL21103
Series:: GSE134388

Download data: TXT

Sample

Accession:: GSM3945612

ID:: 303945612

SRA Run Selector

Select item 3039456115.

B16F10-NTC cells implanted tumor-Mouse 1 [RNA-seq]

Organism:: Mus musculus

Source name:: B16F10-NTC cells implanted tumor-mouse

Platform:: GPL21103
Series:: GSE134388

Download data: TXT

Sample

Accession:: GSM3945611

ID:: 303945611

SRA Run Selector

Select item 3039456106.

B16F10-Fto knockout cells implanted tumor-Mouse 2 [RNA-seq]

Organism:: Mus musculus

Source name:: B16F10-Fto knockout cells implanted tumor-mouse

Platform:: GPL21103
Series:: GSE134388

Download data: TXT

Sample

Accession:: GSM3945610

ID:: 303945610

SRA Run Selector

Select item 3039456097.

B16F10-Fto knockout cells implanted tumor-Mouse 1 [RNA-seq]

Organism:: Mus musculus

Source name:: B16F10-Fto knockout cells implanted tumor-mouse

Platform:: GPL21103
Series:: GSE134388

Download data: TXT

Sample

Accession:: GSM3945609

ID:: 303945609

SRA Run Selector

Select item 3039456088.

B16F10-Alkbh5 knockout cells implanted tumor-Mouse 2 [RNA-seq]

Organism:: Mus musculus

Source name:: B16F10-Alkbh5 knockout cells implanted tumor-mouse

Platform:: GPL21103
Series:: GSE134388

Download data: TXT

Sample

Accession:: GSM3945608

ID:: 303945608

SRA Run Selector

Select item 3039456079.

B16F10-Alkbh5 knockout cells implanted tumor-Mouse 1 [RNA-seq]

Organism:: Mus musculus

Source name:: B16F10-Alkbh5 knockout cells implanted tumor-mouse

Platform:: GPL21103
Series:: GSE134388

Download data: TXT

Sample

Accession:: GSM3945607

ID:: 303945607

SRA Run Selector

Select item 30394560610.

B16F10-NTC cells implanted tumor-Mouse 3 [IP MeRIP-Seq]

Organism:: Mus musculus

Source name:: B16F10-NTC cells implanted tumor-mouse

Platform:: GPL21103
Series:: GSE134388

Sample

Accession:: GSM3945606

ID:: 303945606

SRA Run Selector

Select item 30394560511.

B16F10-NTC cells implanted tumor-Mouse 2 [IP MeRIP-Seq]

Organism:: Mus musculus

Source name:: B16F10-NTC cells implanted tumor-mouse

Platform:: GPL21103
Series:: GSE134388

Sample

Accession:: GSM3945605

ID:: 303945605

SRA Run Selector

Select item 30394560412.

B16F10-NTC cells implanted tumor-Mouse 1 [IP MeRIP-Seq]

Organism:: Mus musculus

Source name:: B16F10-NTC cells implanted tumor-mouse

Platform:: GPL21103
Series:: GSE134388

Sample

Accession:: GSM3945604

ID:: 303945604

SRA Run Selector

Select item 30394560313.

B16F10-Fto knockout cells implanted tumor-Mouse 2 [IP MeRIP-Seq]

Organism:: Mus musculus

Source name:: B16F10-Fto knockout cells implanted tumor-mouse

Platform:: GPL21103
Series:: GSE134388

Sample

Accession:: GSM3945603

ID:: 303945603

SRA Run Selector

Select item 30394560214.

B16F10-Fto knockout cells implanted tumor-Mouse 1 [IP MeRIP-Seq]

Organism:: Mus musculus

Source name:: B16F10-Fto knockout cells implanted tumor-mouse

Platform:: GPL21103
Series:: GSE134388

Sample

Accession:: GSM3945602

ID:: 303945602

SRA Run Selector

Select item 30394560115.

B16F10-Alkbh5 knockout cells implanted tumor-Mouse 2 [IP MeRIP-Seq]

Organism:: Mus musculus

Source name:: B16F10-Alkbh5 knockout cells implanted tumor-mouse

Platform:: GPL21103
Series:: GSE134388

Sample

Accession:: GSM3945601

ID:: 303945601

SRA Run Selector

Select item 30394560016.

B16F10-Alkbh5 knockout cells implanted tumor-Mouse 1 [IP MeRIP-Seq]

Organism:: Mus musculus

Source name:: B16F10-Alkbh5 knockout cells implanted tumor-mouse

Platform:: GPL21103
Series:: GSE134388

Sample

Accession:: GSM3945600

ID:: 303945600

SRA Run Selector

Select item 30394559917.

B16F10-NTC cells implanted tumor-Mouse 3 [Input_MeRIP-Seq]

Organism:: Mus musculus

Source name:: B16F10-NTC cells implanted tumor-mouse

Platform:: GPL21103
Series:: GSE134388

Sample

Accession:: GSM3945599

ID:: 303945599

SRA Run Selector

Select item 30394559818.

B16F10-NTC cells implanted tumor-Mouse 2 [Input_MeRIP-Seq]

Organism:: Mus musculus

Source name:: B16F10-NTC cells implanted tumor-mouse

Platform:: GPL21103
Series:: GSE134388

Sample

Accession:: GSM3945598

ID:: 303945598

SRA Run Selector

Select item 30394559719.

B16F10-NTC cells implanted tumor-Mouse 1 [Input_MeRIP-Seq]

Organism:: Mus musculus

Source name:: B16F10-NTC cells implanted tumor-mouse

Platform:: GPL21103
Series:: GSE134388

Sample

Accession:: GSM3945597

ID:: 303945597

SRA Run Selector

Select item 30394559620.

B16F10-Fto knockout cells implanted tumor-Mouse 2 [Input_MeRIP-Seq]

Organism:: Mus musculus

Source name:: B16F10-Fto knockout cells implanted tumor-mouse

Platform:: GPL21103
Series:: GSE134388

Sample

Accession:: GSM3945596

ID:: 303945596

SRA Run Selector

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