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Items: 14

1.

Thymic epithelial cell alterations and defective thymopoiesis lead to central and peripheral tolerance perturbation in MHCII deficiency

(Submitter supplied) Major Histocompatibility Complex (MHC) class II (MHCII) deficiency, also known as Bare Lymphocyte Syndrome (BLS), is a rare combined immunodeficiency due to mutations in genes regulating expression of MHCII molecules. MHCII deficiency results in impaired cellular and humoral immune responses, leading to severe infections and autoimmunity. The contribution of thymic epithelial cell (TEC) defects to the pathogenesis of this primary immunodeficiency has not been well characterized to date, in particular in regard to immune dysregulation. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21493
12 Samples
Download data: TXT
Series
Accession:
GSE166463
ID:
200166463

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 3000 (Mus musculus)

Organism:
Mus musculus
1132 Series
42459 Samples
Download data
Platform
Accession:
GPL21493
ID:
100021493

3.

mTEC AB0 3

Organism:
Mus musculus
Source name:
medullary thymic epithelial cells (mTECs)
Platform:
GPL21493
Series:
GSE166463
Download data: TXT
Sample
Accession:
GSM5071447
ID:
305071447

SRA Run Selector

4.

mTEC AB0 2

Organism:
Mus musculus
Source name:
medullary thymic epithelial cells (mTECs)
Platform:
GPL21493
Series:
GSE166463
Download data: TXT
Sample
Accession:
GSM5071446
ID:
305071446

SRA Run Selector

5.

mTEC AB0 1

Organism:
Mus musculus
Source name:
medullary thymic epithelial cells (mTECs)
Platform:
GPL21493
Series:
GSE166463
Download data: TXT
Sample
Accession:
GSM5071445
ID:
305071445

SRA Run Selector

6.

mTEC WT 3

Organism:
Mus musculus
Source name:
medullary thymic epithelial cells (mTECs)
Platform:
GPL21493
Series:
GSE166463
Download data: TXT
Sample
Accession:
GSM5071444
ID:
305071444

SRA Run Selector

7.

mTEC WT 2

Organism:
Mus musculus
Source name:
medullary thymic epithelial cells (mTECs)
Platform:
GPL21493
Series:
GSE166463
Download data: TXT
Sample
Accession:
GSM5071443
ID:
305071443

SRA Run Selector

8.

mTEC WT 1

Organism:
Mus musculus
Source name:
medullary thymic epithelial cells (mTECs)
Platform:
GPL21493
Series:
GSE166463
Download data: TXT
Sample
Accession:
GSM5071442
ID:
305071442

SRA Run Selector

9.

cTEC AB0 3

Organism:
Mus musculus
Source name:
cortical thymic epithelial cells (cTECs)
Platform:
GPL21493
Series:
GSE166463
Download data: TXT
Sample
Accession:
GSM5071441
ID:
305071441

SRA Run Selector

10.

cTEC AB0 2

Organism:
Mus musculus
Source name:
cortical thymic epithelial cells (cTECs)
Platform:
GPL21493
Series:
GSE166463
Download data: TXT
Sample
Accession:
GSM5071440
ID:
305071440

SRA Run Selector

11.

cTEC AB0 1

Organism:
Mus musculus
Source name:
cortical thymic epithelial cells (cTECs)
Platform:
GPL21493
Series:
GSE166463
Download data: TXT
Sample
Accession:
GSM5071439
ID:
305071439

SRA Run Selector

12.

cTEC WT 3

Organism:
Mus musculus
Source name:
cortical thymic epithelial cells (cTECs)
Platform:
GPL21493
Series:
GSE166463
Download data: TXT
Sample
Accession:
GSM5071438
ID:
305071438

SRA Run Selector

13.

cTEC WT 2

Organism:
Mus musculus
Source name:
cortical thymic epithelial cells (cTECs)
Platform:
GPL21493
Series:
GSE166463
Download data: TXT
Sample
Accession:
GSM5071437
ID:
305071437

SRA Run Selector

14.

cTEC WT 1

Organism:
Mus musculus
Source name:
cortical thymic epithelial cells (cTECs)
Platform:
GPL21493
Series:
GSE166463
Download data: TXT
Sample
Accession:
GSM5071436
ID:
305071436

SRA Run Selector

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