GSE174153[Accession] - GEO DataSets - NCBI

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Select item 2001741531.

Effects of estradiol supplementation on the brain transcriptome of old rhesus macaques maintained on an obesogenic diet.

(Submitter supplied) Obesity during menopause contributes risk for mood disorders, dementia and Alzheimer’s disease (AD). Given the high prevalence of obesity among postmenopausal women there is an urgent need to evaluate the efficacy of hormone therapy (HT) administered immediately (vs delayed) at menopause in different brain regions involved in memory and cognition. Here, and to more closely replicate the endocrine environment of obese postmenopausal women, either on or off HT, middle-aged female rhesus macaques were ovariectomized/hysterectomized (OvH) and maintained on a high-fat, high-sugar, obesogenic Western-style diet (WSD) for 30 months; half of the animals received HT immediately after OvH and half served as placebo controls. more...

Organism:: Macaca mulatta

Type:: Expression profiling by high throughput sequencing

Platform:: GPL23949
56 Samples

Download data: CSV

Series

Accession:: GSE174153

ID:: 200174153

SRA Run Selector

Select item 1000239492.

Illumina HiSeq 4000 (Macaca mulatta)

Organism:: Macaca mulatta

49 Series
1725 Samples

Platform

Accession:: GPL23949

ID:: 100023949

Select item 3052880383.

Pre-Frontal Cortex sample from subject 43

Organism:: Macaca mulatta

Source name:: Brain - Pre-Frontal Cortex

Platform:: GPL23949
Series:: GSE174153

Sample

Accession:: GSM5288038

ID:: 305288038

SRA Run Selector

Select item 3052880374.

Occipital Cortex sample from subject 43

Organism:: Macaca mulatta

Source name:: Brain - Occipital Cortex

Platform:: GPL23949
Series:: GSE174153

Sample

Accession:: GSM5288037

ID:: 305288037

SRA Run Selector

Select item 3052880365.

Hippocampus sample from subject 43

Organism:: Macaca mulatta

Source name:: Brain - Hippocampus

Platform:: GPL23949
Series:: GSE174153

Sample

Accession:: GSM5288036

ID:: 305288036

SRA Run Selector

Select item 3052880356.

Amygdala sample from subject 43

Organism:: Macaca mulatta

Source name:: Brain - Amygdala

Platform:: GPL23949
Series:: GSE174153

Sample

Accession:: GSM5288035

ID:: 305288035

SRA Run Selector

Select item 3052880347.

Pre-Frontal Cortex sample from subject 42

Organism:: Macaca mulatta

Source name:: Brain - Pre-Frontal Cortex

Platform:: GPL23949
Series:: GSE174153

Sample

Accession:: GSM5288034

ID:: 305288034

SRA Run Selector

Select item 3052880338.

Occipital Cortex sample from subject 42

Organism:: Macaca mulatta

Source name:: Brain - Occipital Cortex

Platform:: GPL23949
Series:: GSE174153

Sample

Accession:: GSM5288033

ID:: 305288033

SRA Run Selector

Select item 3052880329.

Hippocampus sample from subject 42

Organism:: Macaca mulatta

Source name:: Brain - Hippocampus

Platform:: GPL23949
Series:: GSE174153

Sample

Accession:: GSM5288032

ID:: 305288032

SRA Run Selector

Select item 30528803110.

Amygdala sample from subject 42

Organism:: Macaca mulatta

Source name:: Brain - Amygdala

Platform:: GPL23949
Series:: GSE174153

Sample

Accession:: GSM5288031

ID:: 305288031

SRA Run Selector

Select item 30528803011.

Pre-Frontal Cortex sample from subject 41

Organism:: Macaca mulatta

Source name:: Brain - Pre-Frontal Cortex

Platform:: GPL23949
Series:: GSE174153

Sample

Accession:: GSM5288030

ID:: 305288030

SRA Run Selector

Select item 30528802912.

Occipital Cortex sample from subject 41

Organism:: Macaca mulatta

Source name:: Brain - Occipital Cortex

Platform:: GPL23949
Series:: GSE174153

Sample

Accession:: GSM5288029

ID:: 305288029

SRA Run Selector

Select item 30528802813.

Hippocampus sample from subject 41

Organism:: Macaca mulatta

Source name:: Brain - Hippocampus

Platform:: GPL23949
Series:: GSE174153

Sample

Accession:: GSM5288028

ID:: 305288028

SRA Run Selector

Select item 30528802714.

Amygdala sample from subject 41

Organism:: Macaca mulatta

Source name:: Brain - Amygdala

Platform:: GPL23949
Series:: GSE174153

Sample

Accession:: GSM5288027

ID:: 305288027

SRA Run Selector

Select item 30528802615.

Pre-Frontal Cortex sample from subject 40

Organism:: Macaca mulatta

Source name:: Brain - Pre-Frontal Cortex

Platform:: GPL23949
Series:: GSE174153

Sample

Accession:: GSM5288026

ID:: 305288026

SRA Run Selector

Select item 30528802516.

Occipital Cortex sample from subject 40

Organism:: Macaca mulatta

Source name:: Brain - Occipital Cortex

Platform:: GPL23949
Series:: GSE174153

Sample

Accession:: GSM5288025

ID:: 305288025

SRA Run Selector

Select item 30528802417.

Hippocampus sample from subject 40

Organism:: Macaca mulatta

Source name:: Brain - Hippocampus

Platform:: GPL23949
Series:: GSE174153

Sample

Accession:: GSM5288024

ID:: 305288024

SRA Run Selector

Select item 30528802318.

Amygdala sample from subject 40

Organism:: Macaca mulatta

Source name:: Brain - Amygdala

Platform:: GPL23949
Series:: GSE174153

Sample

Accession:: GSM5288023

ID:: 305288023

SRA Run Selector

Select item 30528802219.

Pre-Frontal Cortex sample from subject 39

Organism:: Macaca mulatta

Source name:: Brain - Pre-Frontal Cortex

Platform:: GPL23949
Series:: GSE174153

Sample

Accession:: GSM5288022

ID:: 305288022

SRA Run Selector

Select item 30528802120.

Occipital Cortex sample from subject 39

Organism:: Macaca mulatta

Source name:: Brain - Occipital Cortex

Platform:: GPL23949
Series:: GSE174153

Sample

Accession:: GSM5288021

ID:: 305288021

SRA Run Selector

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