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Items: 1 to 20 of 53

1.

Inherited functional regulatory risk variants for common human cancers [MPRA]

(Submitter supplied) Single nucleotide variants (SNVs) in regulatory DNA are linked to inherited cancer risk. Massively parallel reporter assays (MPRA) of 5,031 SNVs linked to 14 neoplasms comprising >90% of human malignancies were performed in pertinent diploid cell types then integrated with matching chromatin accessibility, looping, and eQTL data to identify 411 regulatory SNVs and their putative target eGenes. The latter highlighted specific protein networks in lifetime cancer risk, including mitochondrial translation, proliferation, signaling, adhesion, and immunity. more...
Organism:
Homo sapiens; synthetic construct
Type:
Other
Platforms:
GPL21697 GPL27609
50 Samples
Download data: FA, TSV
Series
Accession:
GSE183301
ID:
200183301
2.

NextSeq 550 (synthetic construct)

Organism:
synthetic construct
28 Series
593 Samples
Download data
Platform
Accession:
GPL27609
ID:
100027609
3.

NextSeq 550 (Homo sapiens)

Platform
Accession:
GPL21697
ID:
100021697
4.

Thyroid MPRA rep 3 [thy_3]

Organism:
Homo sapiens
Source name:
Thyroid MPRA
Platform:
GPL21697
Series:
GSE183301
Download data
Sample
Accession:
GSM5555283
ID:
305555283
5.

Thyroid MPRA rep 2 [thy_2]

Organism:
Homo sapiens
Source name:
Thyroid MPRA
Platform:
GPL21697
Series:
GSE183301
Download data
Sample
Accession:
GSM5555282
ID:
305555282
6.

Thyroid MPRA rep 1 [thy_1]

Organism:
Homo sapiens
Source name:
Thyroid MPRA
Platform:
GPL21697
Series:
GSE183301
Download data
Sample
Accession:
GSM5555281
ID:
305555281
7.

Renal MPRA rep 3 [renal_3]

Organism:
Homo sapiens
Source name:
Renal MPRA
Platform:
GPL21697
Series:
GSE183301
Download data
Sample
Accession:
GSM5555280
ID:
305555280
8.

Renal MPRA rep 2 [renal_2]

Organism:
Homo sapiens
Source name:
Renal MPRA
Platform:
GPL21697
Series:
GSE183301
Download data
Sample
Accession:
GSM5555279
ID:
305555279
9.

Renal MPRA rep 1 [renal_1]

Organism:
Homo sapiens
Source name:
Renal MPRA
Platform:
GPL21697
Series:
GSE183301
Download data
Sample
Accession:
GSM5555278
ID:
305555278
10.

Prostate MPRA rep 3 [pros_3]

Organism:
Homo sapiens
Source name:
Prostate MPRA
Platform:
GPL21697
Series:
GSE183301
Download data
Sample
Accession:
GSM5555277
ID:
305555277
11.

Prostate MPRA rep 2 [pros_2]

Organism:
Homo sapiens
Source name:
Prostate MPRA
Platform:
GPL21697
Series:
GSE183301
Download data
Sample
Accession:
GSM5555276
ID:
305555276
12.

Prostate MPRA rep 1 [pros_1]

Organism:
Homo sapiens
Source name:
Prostate MPRA
Platform:
GPL21697
Series:
GSE183301
Download data
Sample
Accession:
GSM5555275
ID:
305555275
13.

Pancreas MPRA rep 3 [panc_3]

Organism:
Homo sapiens
Source name:
Pancreas MPRA
Platform:
GPL21697
Series:
GSE183301
Download data
Sample
Accession:
GSM5555274
ID:
305555274
14.

Pancreas MPRA rep 2 [panc_2]

Organism:
Homo sapiens
Source name:
Pancreas MPRA
Platform:
GPL21697
Series:
GSE183301
Download data
Sample
Accession:
GSM5555273
ID:
305555273
15.

Pancreas MPRA rep 1 [panc_1]

Organism:
Homo sapiens
Source name:
Pancreas MPRA
Platform:
GPL21697
Series:
GSE183301
Download data
Sample
Accession:
GSM5555272
ID:
305555272
16.

Ovarian MPRA rep 3 [ov_3]

Organism:
Homo sapiens
Source name:
Ovarian MPRA
Platform:
GPL21697
Series:
GSE183301
Download data
Sample
Accession:
GSM5555271
ID:
305555271
17.

Ovarian MPRA rep 2 [ov_2]

Organism:
Homo sapiens
Source name:
Ovarian MPRA
Platform:
GPL21697
Series:
GSE183301
Download data
Sample
Accession:
GSM5555270
ID:
305555270
18.

Ovarian MPRA rep 1 [ov_1]

Organism:
Homo sapiens
Source name:
Ovarian MPRA
Platform:
GPL21697
Series:
GSE183301
Download data
Sample
Accession:
GSM5555269
ID:
305555269
19.

Melanocyte MPRA rep 3 [mc_3]

Organism:
Homo sapiens
Source name:
Melanocyte MPRA
Platform:
GPL21697
Series:
GSE183301
Download data
Sample
Accession:
GSM5555268
ID:
305555268
20.

Melanocyte MPRA rep 2 [mc_2]

Organism:
Homo sapiens
Source name:
Melanocyte MPRA
Platform:
GPL21697
Series:
GSE183301
Download data
Sample
Accession:
GSM5555267
ID:
305555267
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Supplemental Content

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