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Items: 6

1.

Human Pluripotent Stem Cell-derived Islets Ameliorate Diabetes in Nonhuman Primates [monkey_singlecell]

(Submitter supplied) Human pluripotent stem cell-derived islets (hPSC-islets) are a promising cell resource for diabetes treatment. Here, we demonstrate that transplantation of human pluripotent stem cell-derived islets into diabetic nonhuman primates effectively restored endogenous insulin secretion and improved glycemic control. Single-cell RNA sequencing analysis of S6D2 clusters confirmed the existence of the three major pancreatic endocrine cell populations (β cells, α-like cells and δ-like cells) and their proportions, which altogether accounted for 80%. more...
Organism:
Macaca mulatta
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24522
4 Samples
Download data: CSV, TAR
Series
Accession:
GSE185037
ID:
200185037
2.

HiSeq X Ten (Macaca mulatta)

Organism:
Macaca mulatta
20 Series
652 Samples
Download data
Platform
Accession:
GPL24522
ID:
100024522
3.

PBMCs-8 wpt

Organism:
Macaca mulatta
Source name:
monkey peripheral blood mononuclear cells
Platform:
GPL24522
Series:
GSE185037 GSE185038
Download data: CSV, TAR
Sample
Accession:
GSM5603745
ID:
305603745
4.

PBMCs-4 wpt

Organism:
Macaca mulatta
Source name:
monkey peripheral blood mononuclear cells
Platform:
GPL24522
Series:
GSE185037 GSE185038
Download data: CSV, TAR
Sample
Accession:
GSM5603744
ID:
305603744
5.

PBMCs-Post-IS (Pre-Tx)

Organism:
Macaca mulatta
Source name:
monkey peripheral blood mononuclear cells
Platform:
GPL24522
Series:
GSE185037 GSE185038
Download data: CSV, TAR
Sample
Accession:
GSM5603743
ID:
305603743
6.

PBMCs-Pre-IS

Organism:
Macaca mulatta
Source name:
monkey peripheral blood mononuclear cells
Platform:
GPL24522
Series:
GSE185037 GSE185038
Download data: CSV, TAR
Sample
Accession:
GSM5603742
ID:
305603742
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Supplemental Content

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