GEO DataSets

(Submitter supplied) Background: Genetic studies have been tremendously successful in identifying genomic regions associated with a wide variety of phenotypes, although the success of these studies in identifying causal genes, their variants, and their functional impacts have been more limited.   Methods: We identified 145 genes from IBD-associated genomic loci having endogenous expression within the intestinal epithelial cell compartment.  We evaluated the impact of lentiviral transfer of the open reading frame (ORF) of these IBD genes into the HT-29 intestinal epithelial cell line via transcriptomic analyses.  Comparing the genes whose expression was modulated by each ORF, as well as the functions enriched within these gene lists, identified ORFs with shared impacts and their putative disease-relevant biological functions. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL30867

426 Samples

Download data: TXT

(Submitter supplied) Arrays of this design have barcodes that begin with 16059505 or 2559505. Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. Orientation: Rows and columns are numbered as scanned by an Axon Scanner (barcode on the bottom, DNA on the front surface). more...

Organism:

Homo sapiens

1 Series

426 Samples

Download data: TXT