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Items: 6

1.

COPD and non-diseased nasopharyngeal and bronchial organoids characterization by single cell RNA-seq

(Submitter supplied) Clinical COPD, characterised by intermittent and infective exacerbations, lacks cellular model systems for the study of host-pathogen relationships. We establish nasopharyngeal and bronchial organoids from COPD patients and healthy individuals. In contrast to healthy organoids, COPD organoids demonstrate the hallmark goblet cell hyperplasia phenotype with reduced ciliary beat frequency, leading to impaired mucociliary clearance. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
4 Samples
Download data: MTX, TSV
Series
Accession:
GSE186017
ID:
200186017
2.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
3.

COPD bronchial organoids

Organism:
Homo sapiens
Source name:
Bronchial organoids
Platform:
GPL16791
Series:
GSE186017
Download data: MTX, TSV
Sample
Accession:
GSM5628938
ID:
305628938
4.

Non-diseased bronchial organoids

Organism:
Homo sapiens
Source name:
Bronchial organoids
Platform:
GPL16791
Series:
GSE186017
Download data: MTX, TSV
Sample
Accession:
GSM5628937
ID:
305628937
5.

COPD nasopharyngeal organoids

Organism:
Homo sapiens
Source name:
Nasopharyngeal organoids
Platform:
GPL16791
Series:
GSE186017
Download data: MTX, TSV
Sample
Accession:
GSM5628936
ID:
305628936
6.

Non-diseased nasopharyngeal organoids

Organism:
Homo sapiens
Source name:
Nasopharyngeal organoids
Platform:
GPL16791
Series:
GSE186017
Download data: MTX, TSV
Sample
Accession:
GSM5628935
ID:
305628935
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Supplemental Content

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