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Items: 3

1.

Super-silencer perturbation by EZH2 and REST inhibition leads to large loss of chromatin interactions and reduction in cancer growth [HiChIP]

(Submitter supplied) Human silencers have been shown to exist and regulate developmental gene expression. However, the functional importance of human silencers need to be elucidated such as the working mode and whether they can form “super-silencers”. Here, through interrogating two putative silencer components of FGF18 gene, we found that two silencers can cooperate via compensated chromatin interactions to form the “super-silencer”. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL20301
1 Sample
Download data: BED, HIC
Series
Accession:
GSE193484
ID:
200193484
2.

Illumina HiSeq 4000 (Homo sapiens)

Platform
Accession:
GPL20301
ID:
100020301
3.

K562 H3K27me3 HiChIP

Organism:
Homo sapiens
Source name:
K562 wild type cells
Platform:
GPL20301
Series:
GSE193484 GSE193489
Download data: BED, HIC
Sample
Accession:
GSM5808388
ID:
305808388
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Supplemental Content

db=gds|term=GSE193484[Accession]|query=1|qty=2|blobid=MCID_6673f731ccfbad768f7a3c2e|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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