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Items: 6

1.

The Local Density of H3K9me3 Dictates The Stability of HP1a Condensates-mediated Genomic Interactions

(Submitter supplied) The human genome can be demarcated into different domains based on distinct epigenetic states. The trimethylation of histone H3 lysine 9 (H3K9me3) is essential for the formation of constitutive heterochromatin nanodomains. It is unclear what degrees or densities of H3K9me3 in genomic regions are required for their stable interactions. We demonstrate that the levels of H3K9me3 at the loci are positively correlated with their association with HP1a condensates. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL24676
4 Samples
Download data: BROADPEAK, BW
Series
Accession:
GSE227780
ID:
200227780
2.

Illumina NovaSeq 6000 (Homo sapiens)

Platform
Accession:
GPL24676
ID:
100024676
3.

U2OS-KRAB-IDR3-TCF3, H3K9me3, ABCAM, rep2

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL24676
Series:
GSE227780
Download data: BW
Sample
Accession:
GSM7108086
ID:
307108086
4.

U2OS-KRAB-IDR3-TCF3, H3K9me3, ABCAM, rep1

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL24676
Series:
GSE227780
Download data: BW
Sample
Accession:
GSM7108085
ID:
307108085
5.

U2OS-KRAB-IDR3-TCF3, H3K9me3, ABCAM, input, rep2

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL24676
Series:
GSE227780
Download data: BW
Sample
Accession:
GSM7108084
ID:
307108084
6.

U2OS-KRAB-IDR3-TCF3, H3K9me3, ABCAM, input, rep1

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL24676
Series:
GSE227780
Download data: BW
Sample
Accession:
GSM7108083
ID:
307108083

Supplemental Content

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