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Items: 16

1.

CDK12 prevents MYC-induced transcription-replication conflicts [RNA-seq]

(Submitter supplied) In order to identify genes and pathways necessary to preserve genome integrity upon Myc over-expression, we conducted a large siRNA-based screen in isogenic lines. We discovered several genes that suppressed the Myc-induced DNA-damage response and that were essential for the cell survival upon Myc activation. We idntified CDK12, a cyclin dependent kinase involved in transcriptional control and genome stability. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11154
14 Samples
Download data: BW, XLS
Series
Accession:
GSE236545
ID:
200236545
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

RNA_seq_siCDK12_OHT_rep4

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL11154
Series:
GSE236545 GSE236553
Download data: BW
Sample
Accession:
GSM7549765
ID:
307549765
4.

RNA_seq_siCDK12_OHT_rep3

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL11154
Series:
GSE236545 GSE236553
Download data: BW
Sample
Accession:
GSM7549764
ID:
307549764
5.

RNA_seq_siCDK12_OHT_rep2

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL11154
Series:
GSE236545 GSE236553
Download data: BW
Sample
Accession:
GSM7549763
ID:
307549763
6.

RNA_seq_siCDK12_OHT_rep1

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL11154
Series:
GSE236545 GSE236553
Download data: BW
Sample
Accession:
GSM7549762
ID:
307549762
7.

RNA_seq_siLuc_OHT_rep3

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL11154
Series:
GSE236545 GSE236553
Download data: BW
Sample
Accession:
GSM7549761
ID:
307549761
8.

RNA_seq_siLuc_OHT_rep2

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL11154
Series:
GSE236545 GSE236553
Download data: BW
Sample
Accession:
GSM7549760
ID:
307549760
9.

RNA_seq_siLuc_OHT_rep1

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL11154
Series:
GSE236545 GSE236553
Download data: BW
Sample
Accession:
GSM7549759
ID:
307549759
10.

RNA_seq_siCDK12_rep4

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL11154
Series:
GSE236545 GSE236553
Download data: BW
Sample
Accession:
GSM7549758
ID:
307549758
11.

RNA_seq_siCDK12_rep3

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL11154
Series:
GSE236545 GSE236553
Download data: BW
Sample
Accession:
GSM7549757
ID:
307549757
12.

RNA_seq_siCDK12_rep2

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL11154
Series:
GSE236545 GSE236553
Download data: BW
Sample
Accession:
GSM7549756
ID:
307549756
13.

RNA_seq_siCDK12_rep1

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL11154
Series:
GSE236545 GSE236553
Download data: BW
Sample
Accession:
GSM7549755
ID:
307549755
14.

RNA_seq_siLuc_rep3

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL11154
Series:
GSE236545 GSE236553
Download data: BW
Sample
Accession:
GSM7549754
ID:
307549754
15.

RNA_seq_siLuc_rep2

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL11154
Series:
GSE236545 GSE236553
Download data: BW
Sample
Accession:
GSM7549753
ID:
307549753
16.

RNA_seq_siLuc_rep1

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL11154
Series:
GSE236545 GSE236553
Download data: BW
Sample
Accession:
GSM7549752
ID:
307549752
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