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Items: 14

1.

CDK12 prevents MYC-induced transcription-replication conflicts [EdU-seq]

(Submitter supplied) In order to identify genes and pathways necessary to preserve genome integrity upon Myc over-expression, we conducted a large siRNA-based screen in isogenic lines. We discovered several genes that suppressed the Myc-induced DNA-damage response and that were essential for the cell survival upon Myc activation. We idntified CDK12, a cyclin dependent kinase involved in transcriptional control and genome stability. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL24676
12 Samples
Download data: BED, BW
Series
Accession:
GSE236550
ID:
200236550

PubMed Full text in PMC Similar studies

2.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:
Homo sapiens
17080 Series
933677 Samples
Download data
Platform
Accession:
GPL24676
ID:
100024676

3.

EdU_HU_seq_shCDK12_OHT_rep3

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL24676
Series:
GSE236550 GSE236553
Download data
Sample
Accession:
GSM7549825
ID:
307549825

SRA Run Selector

4.

EdU_HU_seq_shCDK12_OHT_rep2

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL24676
Series:
GSE236550 GSE236553
Download data
Sample
Accession:
GSM7549822
ID:
307549822

SRA Run Selector

5.

EdU_HU_seq_shCDK12_OHT_rep1

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL24676
Series:
GSE236550 GSE236553
Download data
Sample
Accession:
GSM7549819
ID:
307549819

SRA Run Selector

6.

EdU_HU_seq_shCDK12_rep3

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL24676
Series:
GSE236550 GSE236553
Download data
Sample
Accession:
GSM7549817
ID:
307549817

SRA Run Selector

7.

EdU_HU_seq_shCDK12_rep2

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL24676
Series:
GSE236550 GSE236553
Download data
Sample
Accession:
GSM7549815
ID:
307549815

SRA Run Selector

8.

EdU_HU_seq_shCDK12_rep1

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL24676
Series:
GSE236550 GSE236553
Download data
Sample
Accession:
GSM7549814
ID:
307549814

SRA Run Selector

9.

EdU_HU_seq_shNT_OHT_rep3

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL24676
Series:
GSE236550 GSE236553
Download data
Sample
Accession:
GSM7549813
ID:
307549813

SRA Run Selector

10.

EdU_HU_seq_shNT_OHT_rep2

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL24676
Series:
GSE236550 GSE236553
Download data
Sample
Accession:
GSM7549812
ID:
307549812

SRA Run Selector

11.

EdU_HU_seq_shNT_OHT_rep1

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL24676
Series:
GSE236550 GSE236553
Download data
Sample
Accession:
GSM7549811
ID:
307549811

SRA Run Selector

12.

EdU_HU_seq_shNT_rep3

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL24676
Series:
GSE236550 GSE236553
Download data
Sample
Accession:
GSM7549810
ID:
307549810

SRA Run Selector

13.

EdU_HU_seq_shNT_rep2

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL24676
Series:
GSE236550 GSE236553
Download data
Sample
Accession:
GSM7549809
ID:
307549809

SRA Run Selector

14.

EdU_HU_seq_shNT_rep1

Organism:
Homo sapiens
Source name:
U2OS
Platform:
GPL24676
Series:
GSE236550 GSE236553
Download data
Sample
Accession:
GSM7549808
ID:
307549808

SRA Run Selector

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