GSE236581[Accession] - GEO DataSets - NCBI

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Select item 2002365811.

Spatiotemporal single-cell analysis decodes cellular dynamics underlying different responses to immunotherapy in Colorectal Cancer

(Submitter supplied) Expanding the efficacy of immune checkpoint blockade (ICB) in colorectal cancer (CRC) patients presses for a comprehensive understanding of treatment responsiveness. Here, we analyzed 169 single-cell samples from CRC patients at multiple sequential time points during the course of anti-PD-1 neoadjuvant therapy to map the evolution of local and systemic immunity. In tumors, exhausted T (Tex) cells or tumor-reactive-like CD8 T (Ttr-like) cells were closely related to treatment efficacy, and we observed correlated dynamics between Tex cells and multiple other tumor-enriched cell types following the treatment. more...

Organism:: Homo sapiens

Type:: Other

Platform:: GPL24676
169 Samples

Download data: MTX, TSV, TXT

Series

Accession:: GSE236581

ID:: 200236581

PubMed Similar studies

Select item 1000246762.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:: Homo sapiens

16543 Series
922800 Samples

Platform

Accession:: GPL24676

ID:: 100024676

Select item 3075585803.

Organism:: Homo sapiens

Source name:: Tumor

Platform:: GPL24676
Series:: GSE236581

Sample

Accession:: GSM7558580

ID:: 307558580

Select item 3075585784.

Organism:: Homo sapiens

Source name:: Adjacent normal tissue

Platform:: GPL24676
Series:: GSE236581

Sample

Accession:: GSM7558578

ID:: 307558578

Select item 3075585775.

Organism:: Homo sapiens

Source name:: Peripheral blood

Platform:: GPL24676
Series:: GSE236581

Sample

Accession:: GSM7558577

ID:: 307558577

Select item 3075585756.

Organism:: Homo sapiens

Source name:: Tumor

Platform:: GPL24676
Series:: GSE236581

Sample

Accession:: GSM7558575

ID:: 307558575

Select item 3075585747.

Organism:: Homo sapiens

Source name:: Adjacent normal tissue

Platform:: GPL24676
Series:: GSE236581

Sample

Accession:: GSM7558574

ID:: 307558574

Select item 3075585728.

Organism:: Homo sapiens

Source name:: Peripheral blood

Platform:: GPL24676
Series:: GSE236581

Sample

Accession:: GSM7558572

ID:: 307558572

Select item 3075585709.

Organism:: Homo sapiens

Source name:: Tumor

Platform:: GPL24676
Series:: GSE236581

Sample

Accession:: GSM7558570

ID:: 307558570

Select item 30755856910.

Organism:: Homo sapiens

Source name:: Adjacent normal tissue

Platform:: GPL24676
Series:: GSE236581

Sample

Accession:: GSM7558569

ID:: 307558569

Select item 30755856711.

Organism:: Homo sapiens

Source name:: Peripheral blood

Platform:: GPL24676
Series:: GSE236581

Sample

Accession:: GSM7558567

ID:: 307558567

Select item 30755856612.

Organism:: Homo sapiens

Source name:: Tumor

Platform:: GPL24676
Series:: GSE236581

Sample

Accession:: GSM7558566

ID:: 307558566

Select item 30755856413.

Organism:: Homo sapiens

Source name:: Adjacent normal tissue

Platform:: GPL24676
Series:: GSE236581

Sample

Accession:: GSM7558564

ID:: 307558564

Select item 30755856314.

Organism:: Homo sapiens

Source name:: Peripheral blood

Platform:: GPL24676
Series:: GSE236581

Sample

Accession:: GSM7558563

ID:: 307558563

Select item 30755856115.

Organism:: Homo sapiens

Source name:: Tumor

Platform:: GPL24676
Series:: GSE236581

Sample

Accession:: GSM7558561

ID:: 307558561

Select item 30755856016.

Organism:: Homo sapiens

Source name:: Adjacent normal tissue

Platform:: GPL24676
Series:: GSE236581

Sample

Accession:: GSM7558560

ID:: 307558560

Select item 30755855817.

Organism:: Homo sapiens

Source name:: Peripheral blood

Platform:: GPL24676
Series:: GSE236581

Sample

Accession:: GSM7558558

ID:: 307558558

Select item 30755855718.

Organism:: Homo sapiens

Source name:: Tumor

Platform:: GPL24676
Series:: GSE236581

Sample

Accession:: GSM7558557

ID:: 307558557

Select item 30755855519.

Organism:: Homo sapiens

Source name:: Adjacent normal tissue

Platform:: GPL24676
Series:: GSE236581

Sample

Accession:: GSM7558555

ID:: 307558555

Select item 30755855320.

Organism:: Homo sapiens

Source name:: Peripheral blood

Platform:: GPL24676
Series:: GSE236581

Sample

Accession:: GSM7558553

ID:: 307558553

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GSE236581[Accession] (171)
GEO DataSets
major paralogous domain-containing protein [Fibrobacter sp. UWB10]
major paralogous domain-containing protein [Fibrobacter sp. UWB10]
gi|2478927744|emb|SMP52319.1||gnl|W UE|SMP52319

Protein

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