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Items: 14

1.

CEBPA restricts alveolar type 2 cell plasticity during development and injury-repair [1]

(Submitter supplied) Cell plasticity theoretically extends to all possible cell types, but naturally decreases as cells differentiate, whereas injury-repair re-engages the developmental plasticity. Here we show that the lung alveolar type 2 (AT2)-specific transcription factor (TF), CEBPA, restricts AT2 cell plasticity in the mouse lung. AT2 cells undergo transcriptional and epigenetic maturation postnatally. Without CEBPA, both neonatal and mature AT2 cells reduce the AT2 program, but only the former reactivate the SOX9 progenitor program. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL24247
12 Samples
Download data: BROADPEAK, CLOUPE, H5, RDS, TBI, TSV
Series
Accession:
GSE247130
ID:
200247130
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

SeV control scmultiome ATAC

Organism:
Mus musculus
Source name:
lung
Platform:
GPL24247
Series:
GSE247130 GSE247272
Download data
Sample
Accession:
GSM7883987
ID:
307883987
4.

SeV control scmultiome GE

Organism:
Mus musculus
Source name:
lung
Platform:
GPL24247
Series:
GSE247130 GSE247272
Download data
Sample
Accession:
GSM7883986
ID:
307883986
5.

SeV mutant scmultiome ATAC

Organism:
Mus musculus
Source name:
lung
Platform:
GPL24247
Series:
GSE247130 GSE247272
Download data
Sample
Accession:
GSM7883985
ID:
307883985
6.

SeV mutant scmultiome GE

Organism:
Mus musculus
Source name:
lung
Platform:
GPL24247
Series:
GSE247130 GSE247272
Download data
Sample
Accession:
GSM7883984
ID:
307883984
7.

7-wk control scmultiome ATAC

Organism:
Mus musculus
Source name:
lung
Platform:
GPL24247
Series:
GSE247130 GSE247272
Download data: BROADPEAK
Sample
Accession:
GSM7883983
ID:
307883983
8.

7-wk control scmultiome GE

Organism:
Mus musculus
Source name:
lung
Platform:
GPL24247
Series:
GSE247130 GSE247272
Download data
Sample
Accession:
GSM7883982
ID:
307883982
9.

7-wk mutant scmultiome ATAC

Organism:
Mus musculus
Source name:
lung
Platform:
GPL24247
Series:
GSE247130 GSE247272
Download data: BROADPEAK
Sample
Accession:
GSM7883981
ID:
307883981
10.

7 wk mutant scmultiome GE

Organism:
Mus musculus
Source name:
lung
Platform:
GPL24247
Series:
GSE247130 GSE247272
Download data
Sample
Accession:
GSM7883980
ID:
307883980
11.

control P9 scmultiome ATAC

Organism:
Mus musculus
Source name:
lung
Platform:
GPL24247
Series:
GSE247130 GSE247272
Download data: BROADPEAK
Sample
Accession:
GSM7883979
ID:
307883979
12.

control P9 scmultiome GE

Organism:
Mus musculus
Source name:
lung
Platform:
GPL24247
Series:
GSE247130 GSE247272
Download data
Sample
Accession:
GSM7883978
ID:
307883978
13.

mutant P9 scmultiome ATAC

Organism:
Mus musculus
Source name:
lung
Platform:
GPL24247
Series:
GSE247130 GSE247272
Download data: BROADPEAK
Sample
Accession:
GSM7883977
ID:
307883977
14.

mutant P9 scmultiome GE

Organism:
Mus musculus
Source name:
lung
Platform:
GPL24247
Series:
GSE247130 GSE247272
Download data
Sample
Accession:
GSM7883976
ID:
307883976
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Supplemental Content

db=gds|term=GSE247130[Accession]|query=1|qty=2|blobid=MCID_6728de0964a58614144058d4|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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