U.S. flag

An official website of the United States government

Format
Items per page
Sort by

Send to:

Choose Destination

Search results

Items: 1 to 20 of 33

1.

Innate immune activation modulates contractile and electrical dysfunction in engineered heart tissue models fordesmoplakin(DSP)cardiomyopathy.

(Submitter supplied) Desmosomes are specialized cell-cell junctions critically important in the heart, where their disruption promotes arrhythmogenic cardiomyopathy (ACM). Individuals carrying truncating variants in the desmosomal gene desmoplakin (DSP) often show a prominent inflammatory component in the absence of known antigenic stimuli, termed “hot phase” arrythmia. To assess the role of innate immune activation in DSP-cardiomyopathy, we generated engineered heart tissues (EHTs) from two patients with heterozygous DSP truncation variants (DSPtv, p.E1597X and p.R1951X). more...
Organism:
Rattus norvegicus; Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24676 GPL22396
30 Samples
Download data: TXT
Series
Accession:
GSE248187
ID:
200248187
2.

Illumina NovaSeq 6000 (Homo sapiens)

Platform
Accession:
GPL24676
ID:
100024676
3.

Illumina HiSeq 4000 (Rattus norvegicus)

Organism:
Rattus norvegicus
250 Series
4653 Samples
Download data
Platform
Accession:
GPL22396
ID:
100022396
4.

EHTs, DSP+/+ biol rep3

Organism:
Homo sapiens
Source name:
Engineered Heart Tissue
Platform:
GPL24676
Series:
GSE248187
Download data
Sample
Accession:
GSM7907227
ID:
307907227
5.

EHTs, DSP+/+ biol rep2

Organism:
Homo sapiens
Source name:
Engineered Heart Tissue
Platform:
GPL24676
Series:
GSE248187
Download data
Sample
Accession:
GSM7907226
ID:
307907226
6.

EHTs, DSP+/+ biol rep1

Organism:
Homo sapiens
Source name:
Engineered Heart Tissue
Platform:
GPL24676
Series:
GSE248187
Download data
Sample
Accession:
GSM7907225
ID:
307907225
7.

EHTs, DSP-/- biol rep3

Organism:
Homo sapiens
Source name:
Engineered Heart Tissue
Platform:
GPL24676
Series:
GSE248187
Download data
Sample
Accession:
GSM7907224
ID:
307907224
8.

EHTs, DSP-/- biol rep2

Organism:
Homo sapiens
Source name:
Engineered Heart Tissue
Platform:
GPL24676
Series:
GSE248187
Download data
Sample
Accession:
GSM7907223
ID:
307907223
9.

EHTs, DSP-/- biol rep1

Organism:
Homo sapiens
Source name:
Engineered Heart Tissue
Platform:
GPL24676
Series:
GSE248187
Download data
Sample
Accession:
GSM7907222
ID:
307907222
10.

NRVMs, si-RNA Dsp biol rep6

Organism:
Rattus norvegicus
Source name:
NRVM
Platform:
GPL22396
Series:
GSE248187
Download data
Sample
Accession:
GSM7907221
ID:
307907221
11.

NRVMs, si-RNA Dsp biol rep5

Organism:
Rattus norvegicus
Source name:
NRVM
Platform:
GPL22396
Series:
GSE248187
Download data
Sample
Accession:
GSM7907220
ID:
307907220
12.

NRVMs, si-RNA Dsp biol rep4

Organism:
Rattus norvegicus
Source name:
NRVM
Platform:
GPL22396
Series:
GSE248187
Download data
Sample
Accession:
GSM7907219
ID:
307907219
13.

NRVMs, si-RNA Jup biol rep6

Organism:
Rattus norvegicus
Source name:
NRVM
Platform:
GPL22396
Series:
GSE248187
Download data
Sample
Accession:
GSM7907218
ID:
307907218
14.

NRVMs, si-RNA Jup biol rep5

Organism:
Rattus norvegicus
Source name:
NRVM
Platform:
GPL22396
Series:
GSE248187
Download data
Sample
Accession:
GSM7907217
ID:
307907217
15.

NRVMs, si-RNA Jup biol rep4

Organism:
Rattus norvegicus
Source name:
NRVM
Platform:
GPL22396
Series:
GSE248187
Download data
Sample
Accession:
GSM7907216
ID:
307907216
16.

NRVMs, si-RNA Pkp2 biol rep6

Organism:
Rattus norvegicus
Source name:
NRVM
Platform:
GPL22396
Series:
GSE248187
Download data
Sample
Accession:
GSM7907215
ID:
307907215
17.

NRVMs, si-RNA Pkp2 biol rep5

Organism:
Rattus norvegicus
Source name:
NRVM
Platform:
GPL22396
Series:
GSE248187
Download data
Sample
Accession:
GSM7907214
ID:
307907214
18.

NRVMs, si-RNA Pkp2 biol rep4

Organism:
Rattus norvegicus
Source name:
NRVM
Platform:
GPL22396
Series:
GSE248187
Download data
Sample
Accession:
GSM7907213
ID:
307907213
19.

NRVMs, si-RNA scramble biol rep6

Organism:
Rattus norvegicus
Source name:
NRVM
Platform:
GPL22396
Series:
GSE248187
Download data
Sample
Accession:
GSM7907212
ID:
307907212
20.

NRVMs, si-RNA scramble biol rep5

Organism:
Rattus norvegicus
Source name:
NRVM
Platform:
GPL22396
Series:
GSE248187
Download data
Sample
Accession:
GSM7907211
ID:
307907211
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=GSE248187[Accession]|query=12|qty=3|blobid=MCID_672938f191da88433d2030c6|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center