GSE248747[Accession] - GEO DataSets - NCBI

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Items: 13

Select item 2002487471.

Combined absence of Trp53 target genes Zmat3, Puma and p21 cause a high incidence of cancer in mice

(Submitter supplied) Transcriptional activation of target genes is essential for TP53-mediated tumour suppression, though the roles of the diverse TP53-activated target genes in tumour suppression remains poorly understood. Knockdown of Zmat3, an RNA-binding zinc-finger protein involved in regulating alternative splicing, in haematopoietic cells by shRNA caused leukaemia only with the concomitant absence of the Puma and p21, the critical effectors of Trp53-mediated apoptosis and cell cycle arrest respectively. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL30172
11 Samples

Download data: TXT

Series

Accession:: GSE248747

ID:: 200248747

PubMed Full text in PMC Similar studies

Select item 1000301722.

NextSeq 2000 (Mus musculus)

Organism:: Mus musculus

951 Series
16160 Samples

Platform

Accession:: GPL30172

ID:: 100030172

Select item 3079194083.

Zmat3 -/- Puma -/- p21 -/- 3

Organism:: Mus musculus

Source name:: thymus

Platform:: GPL30172
Series:: GSE248747

Sample

Accession:: GSM7919408

ID:: 307919408

SRA Run Selector

Select item 3079194074.

Zmat3 -/- Puma -/- p21 -/- 2

Organism:: Mus musculus

Source name:: thymus

Platform:: GPL30172
Series:: GSE248747

Sample

Accession:: GSM7919407

ID:: 307919407

SRA Run Selector

Select item 3079194065.

Zmat3 -/- Puma -/- p21 -/- 1

Organism:: Mus musculus

Source name:: thymus

Platform:: GPL30172
Series:: GSE248747

Sample

Accession:: GSM7919406

ID:: 307919406

SRA Run Selector

Select item 3079194056.

Organism:: Mus musculus

Source name:: thymus

Platform:: GPL30172
Series:: GSE248747

Sample

Accession:: GSM7919405

ID:: 307919405

SRA Run Selector

Select item 3079194047.

Organism:: Mus musculus

Source name:: thymus

Platform:: GPL30172
Series:: GSE248747

Sample

Accession:: GSM7919404

ID:: 307919404

SRA Run Selector

Select item 3079194038.

Organism:: Mus musculus

Source name:: thymus

Platform:: GPL30172
Series:: GSE248747

Sample

Accession:: GSM7919403

ID:: 307919403

SRA Run Selector

Select item 3079194029.

Organism:: Mus musculus

Source name:: thymus

Platform:: GPL30172
Series:: GSE248747

Sample

Accession:: GSM7919402

ID:: 307919402

SRA Run Selector

Select item 30791940110.

Organism:: Mus musculus

Source name:: thymus

Platform:: GPL30172
Series:: GSE248747

Sample

Accession:: GSM7919401

ID:: 307919401

SRA Run Selector

Select item 30791940011.

Organism:: Mus musculus

Source name:: thymus

Platform:: GPL30172
Series:: GSE248747

Sample

Accession:: GSM7919400

ID:: 307919400

SRA Run Selector

Select item 30791939912.

Organism:: Mus musculus

Source name:: thymus

Platform:: GPL30172
Series:: GSE248747

Sample

Accession:: GSM7919399

ID:: 307919399

SRA Run Selector

Select item 30791939813.

Organism:: Mus musculus

Source name:: thymus

Platform:: GPL30172
Series:: GSE248747

Sample

Accession:: GSM7919398

ID:: 307919398

SRA Run Selector

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