GSE25830[Accession] - GEO DataSets

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Items: 4

Select item 2000258301.

TTF-1-induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma

(Submitter supplied) Adenocarcinoma is the most common histologic subtype of lung cancer, which is the leading cause of cancer death. We and others previously identified TTF-1, a lineage-specific transcription factor required for branching morphogenesis and physiological lung functions, as a lineage-survival oncogene in lung adenocarcinoma. However, how TTF-1 mediates survival signals remains elusive. Here we show that TTF-1 induces receptor tyrosine kinase-like orphan receptor 1 (ROR1), which in turn mediates TTF-1 survival signaling in lung adenocarcinoma. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL1708
2 Samples

Download data: TXT

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Accession:: GSE25830

ID:: 200025830

Select item 1000017082.

Agilent-012391 Whole Human Genome Oligo Microarray G4112A (Feature Number version)

(Submitter supplied) This single 44K formatted microarray represents a compiled view of the human genome as it is understood today. The sequence information used to design this product was derived from a broad survey of well known sources such as RefSeq, Goldenpath, Ensembl, Unigene and others. The resulting view of the human genome covers 41K unique genes and transcripts which have been verified and optimized by alignment to the human genome assembly and by Agilent's Empirical Validation process. more...