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Items: 4

1.

Correlation of antigen expression with epigenetic modifications after rAAV delivery of a human Factor IX variant in mice and rhesus macaques (Tn5 mouse)

(Submitter supplied) We investigated long-term human coagulation Factor IX expression of a novel variant when delivered into mice and rhesus macaques and compare transduction efficiencies using two different AAV capsids. In hemophilic mice injected with KP1-packaged rAAV expressing the hyperactive FIX variant specific activity plasma levels were 10-fold or 2-fold enhanced when compared to wild-type or Padua huFIX injected mice, respectively. more...
Organism:
Mus musculus
Type:
Other
Platform:
GPL24247
2 Samples
Download data: BEDGRAPH
Series
Accession:
GSE261045
ID:
200261045
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

R1-M-48-KP

Organism:
Mus musculus
Source name:
liver
Platform:
GPL24247
Series:
GSE261045 GSE261047
Download data: BEDGRAPH
Sample
Accession:
GSM8133090
ID:
308133090
4.

R1-M-46-KP

Organism:
Mus musculus
Source name:
liver
Platform:
GPL24247
Series:
GSE261045 GSE261047
Download data: BEDGRAPH
Sample
Accession:
GSM8133089
ID:
308133089
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Supplemental Content

db=gds|term=GSE261045[Accession]|query=5|qty=2|blobid=MCID_66a10d3956cb0a044ea3def4|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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