U.S. flag

An official website of the United States government

Format
Items per page
Sort by

Send to:

Choose Destination

Search results

Items: 1 to 20 of 30

1.

Putting the STING back into BH3-mimetic drugs for TP53 mutant blood cancers

(Submitter supplied) TP53-mutant blood cancers remain a major clinical challenge. BH3-mimetic drugs inhibit BCL-2 pro-survival proteins to promote cancer cell apoptosis. Despite acting downstream of TP53, functional TP53 is required for maximal cancer cell killing by BH3-mimetics through an unknown mechanism. Here, we report TP53 can be activated following BH3-mimetic induced mitochondrial outer membrane permeabilization, which leads to induction of BH3-only proteins, thereby potentiating the pro-apoptotic signal. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL30172
28 Samples
Download data: TXT
Series
Accession:
GSE261373
ID:
200261373

2.

NextSeq 2000 (Mus musculus)

Organism:
Mus musculus
980 Series
16495 Samples
Download data
Platform
Accession:
GPL30172
ID:
100030172

3.

AF47A_p53KO_S6

Organism:
Mus musculus
Source name:
Eu-Myc mouse lymphoma
Platform:
GPL30172
Series:
GSE261373
Download data
Sample
Accession:
GSM8141594
ID:
308141594

SRA Run Selector

4.

AF47A_p53KO_DMSO

Organism:
Mus musculus
Source name:
Eu-Myc mouse lymphoma
Platform:
GPL30172
Series:
GSE261373
Download data
Sample
Accession:
GSM8141593
ID:
308141593

SRA Run Selector

5.

AF47A_hBim_S6

Organism:
Mus musculus
Source name:
Eu-Myc mouse lymphoma
Platform:
GPL30172
Series:
GSE261373
Download data
Sample
Accession:
GSM8141592
ID:
308141592

SRA Run Selector

6.

AF47A_hBim_DMSO

Organism:
Mus musculus
Source name:
Eu-Myc mouse lymphoma
Platform:
GPL30172
Series:
GSE261373
Download data
Sample
Accession:
GSM8141591
ID:
308141591

SRA Run Selector

7.

560_StingKO_diABZI_S6

Organism:
Mus musculus
Source name:
Eu-Myc mouse lymphoma
Platform:
GPL30172
Series:
GSE261373
Download data
Sample
Accession:
GSM8141590
ID:
308141590

SRA Run Selector

8.

560_StingKO_diABZI

Organism:
Mus musculus
Source name:
Eu-Myc mouse lymphoma
Platform:
GPL30172
Series:
GSE261373
Download data
Sample
Accession:
GSM8141589
ID:
308141589

SRA Run Selector

9.

560_StingKO_S6

Organism:
Mus musculus
Source name:
Eu-Myc mouse lymphoma
Platform:
GPL30172
Series:
GSE261373
Download data
Sample
Accession:
GSM8141588
ID:
308141588

SRA Run Selector

10.

560_StingKO_DMSO

Organism:
Mus musculus
Source name:
Eu-Myc mouse lymphoma
Platform:
GPL30172
Series:
GSE261373
Download data
Sample
Accession:
GSM8141587
ID:
308141587

SRA Run Selector

11.

560_p53KO_diABZI_S6

Organism:
Mus musculus
Source name:
Eu-Myc mouse lymphoma
Platform:
GPL30172
Series:
GSE261373
Download data
Sample
Accession:
GSM8141586
ID:
308141586

SRA Run Selector

12.

560_p53KO_diABZI

Organism:
Mus musculus
Source name:
Eu-Myc mouse lymphoma
Platform:
GPL30172
Series:
GSE261373
Download data
Sample
Accession:
GSM8141585
ID:
308141585

SRA Run Selector

13.

560_p53KO_S6

Organism:
Mus musculus
Source name:
Eu-Myc mouse lymphoma
Platform:
GPL30172
Series:
GSE261373
Download data
Sample
Accession:
GSM8141584
ID:
308141584

SRA Run Selector

14.

560_p53KO_DMSO

Organism:
Mus musculus
Source name:
Eu-Myc mouse lymphoma
Platform:
GPL30172
Series:
GSE261373
Download data
Sample
Accession:
GSM8141583
ID:
308141583

SRA Run Selector

15.

560_hBim_diABZI_S6

Organism:
Mus musculus
Source name:
Eu-Myc mouse lymphoma
Platform:
GPL30172
Series:
GSE261373
Download data
Sample
Accession:
GSM8141582
ID:
308141582

SRA Run Selector

16.

560_hBim_diABZI

Organism:
Mus musculus
Source name:
Eu-Myc mouse lymphoma
Platform:
GPL30172
Series:
GSE261373
Download data
Sample
Accession:
GSM8141581
ID:
308141581

SRA Run Selector

17.

560_hBim_S6

Organism:
Mus musculus
Source name:
Eu-Myc mouse lymphoma
Platform:
GPL30172
Series:
GSE261373
Download data
Sample
Accession:
GSM8141580
ID:
308141580

SRA Run Selector

18.

560_hBim_DMSO

Organism:
Mus musculus
Source name:
Eu-Myc mouse lymphoma
Platform:
GPL30172
Series:
GSE261373
Download data
Sample
Accession:
GSM8141579
ID:
308141579

SRA Run Selector

19.

AH15A_StingKO_diABZI_S6

Organism:
Mus musculus
Source name:
Eu-Myc mouse lymphoma
Platform:
GPL30172
Series:
GSE261373
Download data
Sample
Accession:
GSM8141578
ID:
308141578

SRA Run Selector

20.

AH15A_StingKO_diABZI

Organism:
Mus musculus
Source name:
Eu-Myc mouse lymphoma
Platform:
GPL30172
Series:
GSE261373
Download data
Sample
Accession:
GSM8141577
ID:
308141577

SRA Run Selector

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filters: Manage Filters

db=gds|term=GSE261373[Accession]|query=1|qty=2|blobid=MCID_6735e047b31eac71f55f22e6|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Important Links

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI > Genes & Expression > Gene Expression Omnibus (GEO) Datasets
Support Center