GSE272312[Accession] - GEO DataSets - NCBI

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Select item 2002723121.

Effect of abemaiclicb and deletion of TP53 on gene expression in MCF7 cells at different timepoints

(Submitter supplied) CDK4/6 inhibitor, abemaciclib induced cell cycle arrest and senescence in breast cancer. We reported that deletion of TP53 prevented the senescence features. In this study, we knockout TP53 by CRISPR Cas9 system and treated MCF7 cells and p53 knockout cells with abemaciclib for up to 29 days to identify the difference of senescence associated secretary phenotype genes and cell cycle related genes. features.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL34281
24 Samples

Download data: TXT

Series

Accession:: GSE272312

ID:: 200272312

Select item 1000342812.

Illumina NovaSeq X (Homo sapiens)

Organism:: Homo sapiens

61 Series
914 Samples

Platform

Accession:: GPL34281

ID:: 100034281

Select item 3083982923.

p53KO, Day 21 rep 3

Organism:: Homo sapiens

Source name:: MCF7

Platform:: GPL34281
Series:: GSE272312

Download data: TXT

Sample

Accession:: GSM8398292

ID:: 308398292

SRA Run Selector

Select item 3083982914.

p53KO, Day 21 rep 2

Organism:: Homo sapiens

Source name:: MCF7

Platform:: GPL34281
Series:: GSE272312

Download data: TXT

Sample

Accession:: GSM8398291

ID:: 308398291

SRA Run Selector

Select item 3083982905.

p53KO, Day 21 rep 1

Organism:: Homo sapiens

Source name:: MCF7

Platform:: GPL34281
Series:: GSE272312

Download data: TXT

Sample

Accession:: GSM8398290

ID:: 308398290

SRA Run Selector

Select item 3083982896.

p53KO, Day 14 rep 3

Organism:: Homo sapiens

Source name:: MCF7

Platform:: GPL34281
Series:: GSE272312

Download data: TXT

Sample

Accession:: GSM8398289

ID:: 308398289

SRA Run Selector

Select item 3083982887.

p53KO, Day 14 rep 2

Organism:: Homo sapiens

Source name:: MCF7

Platform:: GPL34281
Series:: GSE272312

Download data: TXT

Sample

Accession:: GSM8398288

ID:: 308398288

SRA Run Selector

Select item 3083982878.

p53KO, Day 14 rep 1

Organism:: Homo sapiens

Source name:: MCF7

Platform:: GPL34281
Series:: GSE272312

Download data: TXT

Sample

Accession:: GSM8398287

ID:: 308398287

SRA Run Selector

Select item 3083982869.

p53KO, Day 3 rep 3

Organism:: Homo sapiens

Source name:: MCF7

Platform:: GPL34281
Series:: GSE272312

Download data: TXT

Sample

Accession:: GSM8398286

ID:: 308398286

SRA Run Selector

Select item 30839828510.

p53KO, Day 3 rep 2

Organism:: Homo sapiens

Source name:: MCF7

Platform:: GPL34281
Series:: GSE272312

Download data: TXT

Sample

Accession:: GSM8398285

ID:: 308398285

SRA Run Selector

Select item 30839828411.

p53KO, Day 3 rep 1

Organism:: Homo sapiens

Source name:: MCF7

Platform:: GPL34281
Series:: GSE272312

Download data: TXT

Sample

Accession:: GSM8398284

ID:: 308398284

SRA Run Selector

Select item 30839828312.

p53KO, Day 0 rep 3

Organism:: Homo sapiens

Source name:: MCF7

Platform:: GPL34281
Series:: GSE272312

Download data: TXT

Sample

Accession:: GSM8398283

ID:: 308398283

SRA Run Selector

Select item 30839828213.

p53KO, Day 0 rep 2

Organism:: Homo sapiens

Source name:: MCF7

Platform:: GPL34281
Series:: GSE272312

Download data: TXT

Sample

Accession:: GSM8398282

ID:: 308398282

SRA Run Selector

Select item 30839828114.

p53KO, Day 0 rep 1

Organism:: Homo sapiens

Source name:: MCF7

Platform:: GPL34281
Series:: GSE272312

Download data: TXT

Sample

Accession:: GSM8398281

ID:: 308398281

SRA Run Selector

Select item 30839828015.

MCF7 parental, Day 21 rep 3

Organism:: Homo sapiens

Source name:: MCF7

Platform:: GPL34281
Series:: GSE272312

Download data: TXT

Sample

Accession:: GSM8398280

ID:: 308398280

SRA Run Selector

Select item 30839827916.

MCF7 parental, Day 21 rep 2

Organism:: Homo sapiens

Source name:: MCF7

Platform:: GPL34281
Series:: GSE272312

Download data: TXT

Sample

Accession:: GSM8398279

ID:: 308398279

SRA Run Selector

Select item 30839827817.

MCF7 parental, Day 21 rep 1

Organism:: Homo sapiens

Source name:: MCF7

Platform:: GPL34281
Series:: GSE272312

Download data: TXT

Sample

Accession:: GSM8398278

ID:: 308398278

SRA Run Selector

Select item 30839827718.

MCF7 parental, Day 14 rep 3

Organism:: Homo sapiens

Source name:: MCF7

Platform:: GPL34281
Series:: GSE272312

Download data: TXT

Sample

Accession:: GSM8398277

ID:: 308398277

SRA Run Selector

Select item 30839827619.

MCF7 parental, Day 14 rep 2

Organism:: Homo sapiens

Source name:: MCF7

Platform:: GPL34281
Series:: GSE272312

Download data: TXT

Sample

Accession:: GSM8398276

ID:: 308398276

SRA Run Selector

Select item 30839827520.

MCF7 parental, Day 14 rep 1

Organism:: Homo sapiens

Source name:: MCF7

Platform:: GPL34281
Series:: GSE272312

Download data: TXT

Sample

Accession:: GSM8398275

ID:: 308398275

SRA Run Selector

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