GSE276320[Accession] - GEO DataSets - NCBI

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Select item 2002763201.

Chromodomain protein CDYL confers forebrain identity to human cortical organoids by inhibiting neuronatin [RNA-seq]

(Submitter supplied) Epigenetic regulation is essential for the normal development of human cerebral cortex, and its disruptions would lead to diverse neurodevelopmental disorders. The epigenetic co-repressor CDYL exhibits widespread expression across various cell clusters within the human embryonic cortex, yet its roles in this intricate process have remained elusive. Here, we show that CDYL is critical for cortical neurogenesis, and CDYL deficiency led to an augmentation in the generation of GABAergic neurons instead of cortical progenitors and neurons in the cortical organoid model. more...

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL34328 GPL34281
18 Samples

Download data: CSV

Series

Accession:: GSE276320

ID:: 200276320

Select item 1000343282.

Illumina NovaSeq X (Mus musculus)

Organism:: Mus musculus

43 Series
595 Samples

Platform

Accession:: GPL34328

ID:: 100034328

Select item 1000342813.

Illumina NovaSeq X (Homo sapiens)

Organism:: Homo sapiens

61 Series
914 Samples

Platform

Accession:: GPL34281

ID:: 100034281

Select item 3084965594.

Organoid, CDYL KO, Day80, Rep3

Organism:: Homo sapiens

Source name:: Organoid, CDYL KO

Platform:: GPL34281
Series:: GSE276320

Sample

Accession:: GSM8496559

ID:: 308496559

Select item 3084965585.

Organoid, CDYL KO, Day80, Rep2

Organism:: Homo sapiens

Source name:: Organoid, CDYL KO

Platform:: GPL34281
Series:: GSE276320

Sample

Accession:: GSM8496558

ID:: 308496558

Select item 3084965576.

Organoid, CDYL KO, Day80, Rep1

Organism:: Homo sapiens

Source name:: Organoid, CDYL KO

Platform:: GPL34281
Series:: GSE276320

Sample

Accession:: GSM8496557

ID:: 308496557

Select item 3084965567.

Organoid, Control, Day80, Rep3

Organism:: Homo sapiens

Source name:: Organoid, Control

Platform:: GPL34281
Series:: GSE276320

Sample

Accession:: GSM8496556

ID:: 308496556

Select item 3084965558.

Organoid, Control, Day80, Rep2

Organism:: Homo sapiens

Source name:: Organoid, Control

Platform:: GPL34281
Series:: GSE276320

Sample

Accession:: GSM8496555

ID:: 308496555

Select item 3084965549.

Organoid, Control, Day80, Rep1

Organism:: Homo sapiens

Source name:: Organoid, Control

Platform:: GPL34281
Series:: GSE276320

Sample

Accession:: GSM8496554

ID:: 308496554

Select item 30849655310.

Organoid, CDYL KO, Day30, Rep3

Organism:: Homo sapiens

Source name:: Organoid, CDYL KO

Platform:: GPL34281
Series:: GSE276320

Sample

Accession:: GSM8496553

ID:: 308496553

Select item 30849655211.

Organoid, CDYL KO, Day30, Rep2

Organism:: Homo sapiens

Source name:: Organoid, CDYL KO

Platform:: GPL34281
Series:: GSE276320

Sample

Accession:: GSM8496552

ID:: 308496552

Select item 30849655112.

Organoid, CDYL KO, Day30, Rep1

Organism:: Homo sapiens

Source name:: Organoid, CDYL KO

Platform:: GPL34281
Series:: GSE276320

Sample

Accession:: GSM8496551

ID:: 308496551

Select item 30849655013.

Organoid, Control, Day30, Rep3

Organism:: Homo sapiens

Source name:: Organoid, Control

Platform:: GPL34281
Series:: GSE276320

Sample

Accession:: GSM8496550

ID:: 308496550

Select item 30849654914.

Organoid, Control, Day30, Rep2

Organism:: Homo sapiens

Source name:: Organoid, Control

Platform:: GPL34281
Series:: GSE276320

Sample

Accession:: GSM8496549

ID:: 308496549

Select item 30849654815.

Organoid, Control, Day30,Rep1

Organism:: Homo sapiens

Source name:: Organoid, Control

Platform:: GPL34281
Series:: GSE276320

Sample

Accession:: GSM8496548

ID:: 308496548

Select item 30849656516.

Mouse cortex, KO, E15.5, Rep3

Organism:: Mus musculus

Source name:: Mouse, Cortex, Emx1-Cre; CDYLloxp/loxp

Platform:: GPL34328
Series:: GSE276320

Sample

Accession:: GSM8496565

ID:: 308496565

Select item 30849656417.

Mouse cortex, KO, E15.5, Rep2

Organism:: Mus musculus

Source name:: Mouse, Cortex, Emx1-Cre; CDYLloxp/loxp

Platform:: GPL34328
Series:: GSE276320

Sample

Accession:: GSM8496564

ID:: 308496564

Select item 30849656318.

Mouse cortex, KO, E15.5, Rep1

Organism:: Mus musculus

Source name:: Mouse, Cortex, Emx1-Cre; CDYLloxp/loxp

Platform:: GPL34328
Series:: GSE276320

Sample

Accession:: GSM8496563

ID:: 308496563

Select item 30849656219.

Mouse cortex, WT, E15.5, Rep3

Organism:: Mus musculus

Source name:: Mouse, Cortex, CDYLloxp/loxp

Platform:: GPL34328
Series:: GSE276320

Sample

Accession:: GSM8496562

ID:: 308496562

Select item 30849656120.

Mouse cortex, WT, E15.5, Rep2

Organism:: Mus musculus

Source name:: Mouse, Cortex, CDYLloxp/loxp

Platform:: GPL34328
Series:: GSE276320

Sample

Accession:: GSM8496561

ID:: 308496561

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GSE276320[Accession] (21)
GEO DataSets
GSE271460[Accession] (42)
GEO DataSets
Rattus norvegicus methionine sulfoxide reductase B2 (Msrb2), mRNA; nuclear gene ...
Rattus norvegicus methionine sulfoxide reductase B2 (Msrb2), mRNA; nuclear gene for mitochondrial product
gi|2717371454|ref|NM_001031660.2|

Nucleotide
PREDICTED: Rattus norvegicus methionine sulfoxide reductase B2 (Msrb2), transcri...
PREDICTED: Rattus norvegicus methionine sulfoxide reductase B2 (Msrb2), transcript variant X4, mRNA
gi|2678907637|ref|XM_063276662.1|

Nucleotide
syntaxin-12 [Rattus norvegicus]
syntaxin-12 [Rattus norvegicus]
gi|77695930|ref|NP_075228.2|

Protein

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