GEO DataSets

(Submitter supplied) Structural analogues are assumed to elicit toxicity via similar predominant modes of action (MOAs). Currently, MOA categorization of chemicals in environmental risk assessment is mainly based on the physico-chemical properties of potential toxicants. It is often not known whether such classification schemes are also supported by mechanistic biological data. In this study, the toxic effects of two groups of structural analogues (alcohols and anilines) with predefined MOA (narcotics and polar narcotics) were investigated at different levels of biological organization (gene transcription, energy reserves and growth). more...

Organism:

Daphnia magna

Type:

Expression profiling by array

Platform:

GPL13463

9 Samples

Download data: GPR

(Submitter supplied) This microarray is composed of 3 cDNA libraries which are the result of 3 SSH procedures. One SSH was performed with adult vs juvenile gene pools, one with ecdyson exposed vs control organisms and one with starved vs well fed organisms (Soetaert et al., 2006; 2007). The unique sequences selected via those SSHs were supplemented with additional set of unique gene fragments related selected through 3 other SSHs related to other stress factors (fish, Pasteuria ramosa and carbaryl stress) (Orsine et al., 2011). more...

Organism:

Daphnia magna

8 Series

63 Samples

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