GSE3312[Accession] - GEO DataSets

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Items: 6

Select item 2000033121.

Expression Changes Relevant for Apoptosis in K562 Cells Co-Treated with Amifostine and Imatinib

(Submitter supplied) We had previously demonstrated an increased proapoptotic effect of Imatinib (STI571) in combination with Amifostine (AMI) in K562 cell line. In this study we used genomic scale gene expression profiling to monitor changes at transcriptional level in K562 cells during the treatment with AMI+STI571. We identified a transcriptional repressor of survival genes, known as BTF, which triggers a pro-apoptotic signal, potentially helpful to overcome the resistance to STI571. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL2829
4 Samples

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Series

Accession:: GSE3312

ID:: 200003312

Select item 1000028292.

UHN SS-Human 19Kv7

(Submitter supplied) Microarrays are printed on UltraGAPS™ slides (Corning Inc.) using high-precision robotics. Printed arrays are processed following Corning's protocol and are ready-to-use. Single-spotted array containing 19,008 characterized and unknown human ESTs. The clone set has been sequence-verified at the Microarray Centre After printing, the slides are subjected to processing and performance testing based on true labelling, hybridization and scanning procedures. more...