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Items: 1 to 20 of 49

1.

Loss of imprinting at the CTCF binding sites in the DLK1-DIO3 domain reactivates microRNA expression in acute promyelocytic leukaemia

(Submitter supplied) We report the DNA-methylation profiling of 10 regions selected from the DLK1-DIO3 domain on chromosome 14q32 in BM/PB samples from patients with acute promyelocytic leukaemia (APL), other subclasses of acute myeloid leukaemia and healthy donors, using high-throughput amplicon bisulfite sequencing with Roche 454 technology. We identify monoallelic-hypermethylation in APL only at the differentially methylated region (DMR) located upstream from the MEG3 gene (MEG3-DMR), whereas no changes in the DNA methylation profile were detected at the imprinting control region of the domain (IG-DMR) among the samples analysed. more...
Organism:
Homo sapiens
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL14603
47 Samples
Download data: TXT, WIG
Series
Accession:
GSE42543
ID:
200042543
2.

454 GS FLX Titanium (Homo sapiens)

Organism:
Homo sapiens
13 Series
146 Samples
Download data
Platform
Accession:
GPL14603
ID:
100014603
3.

Control_57

Organism:
Homo sapiens
Source name:
Peripheral Blood
Platform:
GPL14603
Series:
GSE42543
Download data: WIG
Sample
Accession:
GSM1044748
ID:
301044748
4.

Control_56

Organism:
Homo sapiens
Source name:
Peripheral Blood
Platform:
GPL14603
Series:
GSE42543
Download data: WIG
Sample
Accession:
GSM1044747
ID:
301044747
5.

Control_55

Organism:
Homo sapiens
Source name:
Peripheral Blood
Platform:
GPL14603
Series:
GSE42543
Download data: WIG
Sample
Accession:
GSM1044746
ID:
301044746
6.

Control_54

Organism:
Homo sapiens
Source name:
Peripheral Blood
Platform:
GPL14603
Series:
GSE42543
Download data: WIG
Sample
Accession:
GSM1044745
ID:
301044745
7.

Control_53

Organism:
Homo sapiens
Source name:
Bone Marrow Mononuclear Cells
Platform:
GPL14603
Series:
GSE42543
Download data: WIG
Sample
Accession:
GSM1044744
ID:
301044744
8.

Control_52

Organism:
Homo sapiens
Source name:
Bone Marrow Mononuclear Cells
Platform:
GPL14603
Series:
GSE42543
Download data: WIG
Sample
Accession:
GSM1044743
ID:
301044743
9.

Control_51

Organism:
Homo sapiens
Source name:
Bone Marrow
Platform:
GPL14603
Series:
GSE42543
Download data: WIG
Sample
Accession:
GSM1044742
ID:
301044742
10.

Control_50

Organism:
Homo sapiens
Source name:
Bone Marrow
Platform:
GPL14603
Series:
GSE42543
Download data: WIG
Sample
Accession:
GSM1044741
ID:
301044741
11.

Control_46

Organism:
Homo sapiens
Source name:
Bone Marrow
Platform:
GPL14603
Series:
GSE42543
Download data: WIG
Sample
Accession:
GSM1044740
ID:
301044740
12.

Control_45

Organism:
Homo sapiens
Source name:
Bone Marrow
Platform:
GPL14603
Series:
GSE42543
Download data: WIG
Sample
Accession:
GSM1044739
ID:
301044739
13.

AML_42

Organism:
Homo sapiens
Source name:
Leukapheresis
Platform:
GPL14603
Series:
GSE42543
Download data: WIG
Sample
Accession:
GSM1044738
ID:
301044738
14.

AML_41

Organism:
Homo sapiens
Source name:
Bone Marrow
Platform:
GPL14603
Series:
GSE42543
Download data: WIG
Sample
Accession:
GSM1044737
ID:
301044737
15.

AML_40

Organism:
Homo sapiens
Source name:
Peripheral Blood
Platform:
GPL14603
Series:
GSE42543
Download data: WIG
Sample
Accession:
GSM1044736
ID:
301044736
16.

AML_39

Organism:
Homo sapiens
Source name:
Leukapheresis
Platform:
GPL14603
Series:
GSE42543
Download data: WIG
Sample
Accession:
GSM1044735
ID:
301044735
17.

AML_38

Organism:
Homo sapiens
Source name:
Peripheral Blood
Platform:
GPL14603
Series:
GSE42543
Download data: WIG
Sample
Accession:
GSM1044734
ID:
301044734
18.

AML_37

Organism:
Homo sapiens
Source name:
Peripheral Blood
Platform:
GPL14603
Series:
GSE42543
Download data: WIG
Sample
Accession:
GSM1044733
ID:
301044733
19.

APL_35

Organism:
Homo sapiens
Source name:
Peripheral Blood
Platform:
GPL14603
Series:
GSE42543
Download data: WIG
Sample
Accession:
GSM1044732
ID:
301044732
20.

APL_33

Organism:
Homo sapiens
Source name:
Leukapheresis
Platform:
GPL14603
Series:
GSE42543
Download data: WIG
Sample
Accession:
GSM1044731
ID:
301044731
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Supplemental Content

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