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Items: 14

1.

CBFb Stabilizes HIV Vif to Counteract APOBEC3 at the Expense of RUNX1 Target Gene Expression [gene expression]

(Submitter supplied) The HIV-1 accessory protein Vif hijacks a cellular Cullin-RING ubiquitin ligase, CRL5, to promote degradation of the APOBEC3 (A3) family of restriction factors. Recently, the cellular transcription cofactor CBFb was shown to form a complex with CRL5-Vif and to be essential for A3 degradation and viral infectivity. We now demonstrate that CBFb is required for assembling a well-ordered CRL5-Vif complex by inhibiting Vif oligomerization and by activating CRL5-Vif via direct interaction. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL16332
12 Samples
Download data: CEL
Series
Accession:
GSE42574
ID:
200042574

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [MMBGX-Ensembl64]

(Submitter supplied) This platform contains certain probeset groupings used for analysis with the MMBGX software platform (PMID 19854940) http://www.bgx.org.uk/software/mmbgx.html For data processing, the MMBGX software suite uses raw data CEL files directly as input. Protocol: See manufacturer's web site
Organism:
Homo sapiens
2 Series
1 Related Platform
12 Samples
Download data
Platform
Accession:
GPL16332
ID:
100016332

3.

vif_6hrs_rep3

Organism:
Homo sapiens
Source name:
Jurkat Trex expressing Vif_6hrs PMA/PHA
Platform:
GPL16332
Series:
GSE42574 GSE42576
Download data: CEL
Sample
Accession:
GSM1045362
ID:
301045362

4.

vif_6hrs_rep2

Organism:
Homo sapiens
Source name:
Jurkat Trex expressing Vif_6hrs PMA/PHA
Platform:
GPL16332
Series:
GSE42574 GSE42576
Download data: CEL
Sample
Accession:
GSM1045361
ID:
301045361

5.

vif_6hrs_rep1

Organism:
Homo sapiens
Source name:
Jurkat Trex expressing Vif_6hrs PMA/PHA
Platform:
GPL16332
Series:
GSE42574 GSE42576
Download data: CEL
Sample
Accession:
GSM1045360
ID:
301045360

6.

vif_4hrs_rep3

Organism:
Homo sapiens
Source name:
Jurkat Trex expressing Vif_4hrs PMA/PHA
Platform:
GPL16332
Series:
GSE42574 GSE42576
Download data: CEL
Sample
Accession:
GSM1045359
ID:
301045359

7.

vif_4hrs_rep2

Organism:
Homo sapiens
Source name:
Jurkat Trex expressing Vif_4hrs PMA/PHA
Platform:
GPL16332
Series:
GSE42574 GSE42576
Download data: CEL
Sample
Accession:
GSM1045358
ID:
301045358

8.

vif_4hrs_rep1

Organism:
Homo sapiens
Source name:
Jurkat Trex expressing Vif_4hrs PMA/PHA
Platform:
GPL16332
Series:
GSE42574 GSE42576
Download data: CEL
Sample
Accession:
GSM1045357
ID:
301045357

9.

reference_6hrs_rep3

Organism:
Homo sapiens
Source name:
Jurkat Trex_6hrs PMA/PHA
Platform:
GPL16332
Series:
GSE42574 GSE42576
Download data: CEL
Sample
Accession:
GSM1045356
ID:
301045356

10.

reference_6hrs_rep2

Organism:
Homo sapiens
Source name:
Jurkat Trex_6hrs PMA/PHA
Platform:
GPL16332
Series:
GSE42574 GSE42576
Download data: CEL
Sample
Accession:
GSM1045355
ID:
301045355

11.

reference_6hrs_rep1

Organism:
Homo sapiens
Source name:
Jurkat Trex_6hrs PMA/PHA
Platform:
GPL16332
Series:
GSE42574 GSE42576
Download data: CEL
Sample
Accession:
GSM1045354
ID:
301045354

12.

reference_4hrs_rep3

Organism:
Homo sapiens
Source name:
Jurkat Trex_4hrs PMA/PHA
Platform:
GPL16332
Series:
GSE42574 GSE42576
Download data: CEL
Sample
Accession:
GSM1045353
ID:
301045353

13.

reference_4hrs_rep2

Organism:
Homo sapiens
Source name:
Jurkat Trex_4hrs PMA/PHA
Platform:
GPL16332
Series:
GSE42574 GSE42576
Download data: CEL
Sample
Accession:
GSM1045352
ID:
301045352

14.

reference_4hrs_rep1

Organism:
Homo sapiens
Source name:
Jurkat Trex_4hrs PMA/PHA
Platform:
GPL16332
Series:
GSE42574 GSE42576
Download data: CEL
Sample
Accession:
GSM1045351
ID:
301045351

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