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Items: 6

1.

In vivo live imaging of RNA polymerase II transcription factories in primary cells

(Submitter supplied) Transcription steps are marked by different modifications of the C-terminal domain of RNA polymerase II (RNAPII). Phosphorylation of Ser5 and Ser7 by cyclin-dependent kinase 7 (CDK7) as part of TFIIH marks initiation, whereas phosphorylation of Ser2 by CDK9 marks elongation. These processes are thought to take place in localized transcription foci in the nucleus, known as ‘‘transcription factories,’’ but it has been argued that the observed clusters/foci are mere fixation or labeling artifacts. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL13112
4 Samples
Download data: BIGWIG
Series
Accession:
GSE46849
ID:
200046849
2.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
3.

IgG_Control_RNAPII

Organism:
Mus musculus
Source name:
Murine erythroleukemia (MEL) cells
Platform:
GPL13112
Series:
GSE46849
Download data
Sample
Accession:
GSM1139142
ID:
301139142
4.

IgG_Control_Cdk9

Organism:
Mus musculus
Source name:
Murine erythroleukemia (MEL) cells
Platform:
GPL13112
Series:
GSE46849
Download data
Sample
Accession:
GSM1139141
ID:
301139141
5.

RNAPII_ChIPSeq

Organism:
Mus musculus
Source name:
Murine erythroleukemia (MEL) cells
Platform:
GPL13112
Series:
GSE46849
Download data: BIGWIG
Sample
Accession:
GSM1139140
ID:
301139140
6.

Cdk9_ChIPSeq

Organism:
Mus musculus
Source name:
Murine erythroleukemia (MEL) cells
Platform:
GPL13112
Series:
GSE46849
Download data: BIGWIG
Sample
Accession:
GSM1139139
ID:
301139139
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Supplemental Content

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