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Items: 6

1.

CHD5 is required for neurogenesis and has a dual role in facilitating gene expression and Polycomb gene repression

(Submitter supplied) The chromatin remodeler CHD5 is expressed in neural tissue and is frequently deleted in aggressive neuroblastoma. Very little is known about the function of CHD5 in the nervous system or its mechanism of action. Here we report that depletion of Chd5 in the developing murine neocortex blocks neuronal differentiation and leads to an accumulation of undifferentiated progenitors. CHD5 binds a large cohort of genes and is required for facilitating the activation of neuronal genes. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL11154
4 Samples
Download data: BED, TDF
Series
Accession:
GSE48314
ID:
200048314
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

Input_DNA

Organism:
Homo sapiens
Source name:
FBio-CHD5 expressing SH-SY5Y cells
Platform:
GPL11154
Series:
GSE48314
Download data: TDF
Sample
Accession:
GSM1174717
ID:
301174717
4.

H3K27me3_ChIPSeq

Organism:
Homo sapiens
Source name:
FBio-CHD5 expressing SH-SY5Y cells
Platform:
GPL11154
Series:
GSE48314
Download data: TDF
Sample
Accession:
GSM1174716
ID:
301174716
5.

Fbio-Ctrl_ChIPSeq

Organism:
Homo sapiens
Source name:
Fbio-Ctrl expressing SH-SY5Y cells
Platform:
GPL11154
Series:
GSE48314
Download data: TDF
Sample
Accession:
GSM1174715
ID:
301174715
6.

FBio-CHD5_ChIPSeq

Organism:
Homo sapiens
Source name:
FBio-CHD5 expressing SH-SY5Y cells
Platform:
GPL11154
Series:
GSE48314
Download data: TDF
Sample
Accession:
GSM1174714
ID:
301174714
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Supplemental Content

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