GEO DataSets

(Submitter supplied) Azaspiracid-1 (AZA-1) is a marine phycotoxin that accumulates in shellfish and known to cause severe gastrointestinal intoxications in humans. As the mechanism of action of AZA-1 is currently unknown, human DNA microarrays were used to profile gene expression in human lymphocyte T cells following AZA-1 exposure. Highly significant early (1 hr) genes consisted of a T cell specific transcription factor, membrane proteins, receptors, and inflammatory genes. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS3433

Platform:

GPL1708

6 Samples

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Analysis of T lymphocyte Jurkat cells treated with 10 nM azaspiracid-1 (AZA-1) for up to 24 hours. AZA-1 is a marine biotoxin reported to accumulate in shellfish and is associated with severe gastrointestinal human intoxication. Results provide insight into the mechanism of action of AZA-1.

Organism:

Homo sapiens

Type:

Expression profiling by array, log10 ratio, 3 time sets

Platform:

GPL1708

Series:

GSE5346

6 Samples

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(Submitter supplied) This single 44K formatted microarray represents a compiled view of the human genome as it is understood today. The sequence information used to design this product was derived from a broad survey of well known sources such as RefSeq, Goldenpath, Ensembl, Unigene and others. The resulting view of the human genome covers 41K unique genes and transcripts which have been verified and optimized by alignment to the human genome assembly and by Agilent's Empirical Validation process. more...

Organism:

Homo sapiens

6 DataSets

136 Series

1 Related Platform

3292 Samples

Download data: TXT