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Items: 8

1.

mRNA profiling reveals determinants of trastuzumab efficiency in HER2-positive breast cancer

(Submitter supplied) The intention was to detect genes that are determining trastuzumab efficiency in HER2-positive breast cancer cell lines with different resistance phenotypes. While BT474 should be sensitive to the drug treatment, HCC1954 is expected to be resistant due to a PI3K mutation. The cell line BTR50 has been derived from BT474 and was cultured to be resistant as well. Based on RNA-Seq data, we performed differential expression analyses on these breast cancer cell lines with and without trastuzumab treatment. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11154
6 Samples
Download data: XLS
Series
Accession:
GSE55005
ID:
200055005

PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector

2.

Illumina HiSeq 2000 (Homo sapiens)

Organism:
Homo sapiens
10522 Series
183330 Samples
Download data
Platform
Accession:
GPL11154
ID:
100011154

3.

Trastuzumab resistant version of the human BT474 breast cancer cell line under trastuzumab treatment

Organism:
Homo sapiens
Source name:
Cell line
Platform:
GPL11154
Series:
GSE55005
Download data
Sample
Accession:
GSM1327858
ID:
301327858

SRA Run Selector

4.

Trastuzumab resistant version of the human BT474 breast cancer cell line

Organism:
Homo sapiens
Source name:
Cell line
Platform:
GPL11154
Series:
GSE55005
Download data
Sample
Accession:
GSM1327857
ID:
301327857

SRA Run Selector

5.

Human HCC1954 breast cancer cell line under trastuzumab treatment

Organism:
Homo sapiens
Source name:
Cell line
Platform:
GPL11154
Series:
GSE55005
Download data
Sample
Accession:
GSM1327856
ID:
301327856

SRA Run Selector

6.

Human HCC1954 breast cancer cell line

Organism:
Homo sapiens
Source name:
Cell line
Platform:
GPL11154
Series:
GSE55005
Download data
Sample
Accession:
GSM1327855
ID:
301327855

SRA Run Selector

7.

Human BT474 breast cancer cell line under trastuzumab treatment

Organism:
Homo sapiens
Source name:
Cell line
Platform:
GPL11154
Series:
GSE55005
Download data
Sample
Accession:
GSM1327854
ID:
301327854

SRA Run Selector

8.

Human BT474 breast cancer cell line

Organism:
Homo sapiens
Source name:
Cell line
Platform:
GPL11154
Series:
GSE55005
Download data
Sample
Accession:
GSM1327853
ID:
301327853

SRA Run Selector

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db=gds|term=GSE55005[Accession]|query=1|qty=2|blobid=MCID_6708483d475a635e8582079a|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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