GSE57073[Accession] - GEO DataSets - NCBI

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Items: 8

Select item 2000570731.

Irp2 mediates cigarette smoke-induced bronchitis and emphysema via regulation of cytochrome c oxidase and mitochondrial iron loading

(Submitter supplied) Chronic obstructive pulmonary disease (COPD), the fourth leading cause of death globally, is influenced by both cigarette smoking and genetic determinants. We have previously identified iron-responsive element binding protein 2 (IRP2) as a candidate COPD susceptibility gene based on genetic association studies, with IRP2 increased in the lungs of COPD patients. Here we demonstrate that mice deficient in IRP2 are protected from cigarette smoke (CS)-induced COPD. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11154
6 Samples

Download data: TXT

Series

Accession:: GSE57073

ID:: 200057073

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 1000111542.

Illumina HiSeq 2000 (Homo sapiens)

Organism:: Homo sapiens

10434 Series
180667 Samples

Platform

Accession:: GPL11154

ID:: 100011154

Select item 3013740963.

Immunoprecipitation with IGG antibody from cells treated with DFO

Organism:: Homo sapiens

Source name:: human bronchial epithelial cells (Beas2B cells)

Platform:: GPL11154
Series:: GSE57073

Sample

Accession:: GSM1374096

ID:: 301374096

SRA Run Selector

Select item 3013740954.

IRP2 immunoprecipitation from cells treated with DFO, replicate 2

Organism:: Homo sapiens

Source name:: human bronchial epithelial cells (Beas2B cells)

Platform:: GPL11154
Series:: GSE57073

Sample

Accession:: GSM1374095

ID:: 301374095

SRA Run Selector

Select item 3013740945.

IRP2 immunoprecipitation from cells treated with DFO, replicate 1

Organism:: Homo sapiens

Source name:: human bronchial epithelial cells (Beas2B cells)

Platform:: GPL11154
Series:: GSE57073

Sample

Accession:: GSM1374094

ID:: 301374094

SRA Run Selector

Select item 3013740936.

Immunoprecipitation with IGG antibody from untreated cells

Organism:: Homo sapiens

Source name:: human bronchial epithelial cells (Beas2B cells)

Platform:: GPL11154
Series:: GSE57073

Sample

Accession:: GSM1374093

ID:: 301374093

SRA Run Selector

Select item 3013740927.

IRP2 immunoprecipitation from untreated cells, replicate 2

Organism:: Homo sapiens

Source name:: human bronchial epithelial cells (Beas2B cells)

Platform:: GPL11154
Series:: GSE57073

Sample

Accession:: GSM1374092

ID:: 301374092

SRA Run Selector

Select item 3013740918.

IRP2 immunoprecipitation from untreated cells, replicate 1

Organism:: Homo sapiens

Source name:: human bronchial epithelial cells (Beas2B cells)

Platform:: GPL11154
Series:: GSE57073

Sample

Accession:: GSM1374091

ID:: 301374091

SRA Run Selector

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