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Items: 6

1.

H3K9 methyltransferase G9a negatively regulates UHRF1 transdcription during leukemia cell differentiation.

(Submitter supplied) Posttranslational modifications of histone N-terminal tails influence the status of chromatin and eventually control the transcriptional outcome of a particular gene. As a histone H3K9 methyltransferase (HMTase) in higher eukaryotes, G9a-mediated transcriptional repression is the major epigenetic silencing machinery. UHRF1 (ubiquitin-like with PHD and ring finger domains I) binds to hemi-methylated DNA and plays essential role in maintenance of DNA methylation by recruiting DNMT1. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL10999
4 Samples
Download data: BIGWIG
Series
Accession:
GSE63149
ID:
200063149
2.

Illumina Genome Analyzer IIx (Homo sapiens)

Platform
Accession:
GPL10999
ID:
100010999
3.

Acetyl-H3_ChIPSeq, TPA-treated HL-60 cells

Organism:
Homo sapiens
Source name:
Peripheral blood leukocytes
Platform:
GPL10999
Series:
GSE63149
Download data: BIGWIG
Sample
Accession:
GSM1542196
ID:
301542196
4.

Acetyl-H3_ChIPSeq, DMSO-treated HL-60 cells

Organism:
Homo sapiens
Source name:
Peripheral blood leukocytes
Platform:
GPL10999
Series:
GSE63149
Download data: BIGWIG
Sample
Accession:
GSM1542195
ID:
301542195
5.

PolII_ChIPSeq, TPA-treated HL-60 cells

Organism:
Homo sapiens
Source name:
Peripheral blood leukocytes
Platform:
GPL10999
Series:
GSE63149
Download data: BIGWIG
Sample
Accession:
GSM1542194
ID:
301542194
6.

PolII_ChIPSeq, DMSO-treated HL-60 cells

Organism:
Homo sapiens
Source name:
Peripheral blood leukocytes
Platform:
GPL10999
Series:
GSE63149
Download data: BIGWIG
Sample
Accession:
GSM1542193
ID:
301542193
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Supplemental Content

db=gds|term=GSE63149[Accession]|query=14|qty=2|blobid=MCID_671f8f763b96c123901b29d0|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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