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Items: 12

1.

Distinct activities of Myf5 and MyoD indicate sequential roles in skeletal muscle lineage specification and differentiation (ChIP-Seq)

(Submitter supplied) In this work we compare the molecular functions of Myf5 and MyoD, two highly related bHLH transcription factors that regulate skeletal muscle specification and differentiation. We find MyoD and Myf5 bind the same sites genome-wide but have distinct functions: Myf5 induces histone acetylation without Pol II recruitment or robust gene activation, whereas MyoD induces histone acetylation, recruits PolII and robustly activates gene transcription.
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL17021
10 Samples
Download data: CSV
Series
Accession:
GSE75370
ID:
200075370
2.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
3.

H4Ac_Myf5_input

Organism:
Mus musculus
Source name:
ChIP-Seq with no antibody in mouse M&M MEF cells transduced with Myf5
Platform:
GPL17021
Series:
GSE75370 GSE75632
Download data
Sample
Accession:
GSM1954040
ID:
301954040
4.

H4Ac_MyoD_input

Organism:
Mus musculus
Source name:
ChIP-Seq with no antibody in mouse M&M MEF cells transduced with MyoD
Platform:
GPL17021
Series:
GSE75370 GSE75632
Download data
Sample
Accession:
GSM1954039
ID:
301954039
5.

H4Ac_GFP_inut

Organism:
Mus musculus
Source name:
ChIP-Seq with no antibody in mouse M&M MEF cells transduced with GFP
Platform:
GPL17021
Series:
GSE75370 GSE75632
Download data
Sample
Accession:
GSM1954038
ID:
301954038
6.

Mock_Myf5_ChIP

Organism:
Mus musculus
Source name:
ChIP-Seq with Myf5 antibody Sc-302x (lot CO612) in mouse M&M MEF cells transduced with GFP
Platform:
GPL17021
Series:
GSE75370 GSE75632
Download data: CSV
Sample
Accession:
GSM1954037
ID:
301954037
7.

Mock_MyoD_ChIP

Organism:
Mus musculus
Source name:
ChIP-Seq with MyoD antibody 6975 in mouse M&M MEF cells transduced with GFP
Platform:
GPL17021
Series:
GSE75370 GSE75632
Download data: CSV
Sample
Accession:
GSM1954036
ID:
301954036
8.

H4Ac_Myf5

Organism:
Mus musculus
Source name:
ChIP-Seq with H4Ac antibody 39925 in mouse M&M MEF cells transduced with Myf5
Platform:
GPL17021
Series:
GSE75370 GSE75632
Download data: CSV
Sample
Accession:
GSM1954035
ID:
301954035
9.

H4Ac_MyoD

Organism:
Mus musculus
Source name:
ChIP-Seq with H4Ac antibody 39925 in mouse M&M MEF cells transduced with MyoD
Platform:
GPL17021
Series:
GSE75370 GSE75632
Download data: CSV
Sample
Accession:
GSM1954034
ID:
301954034
10.

H4Ac_GFP

Organism:
Mus musculus
Source name:
ChIP-Seq with H4Ac antibody 39925 in mouse M&M MEF cells transduced with GFP
Platform:
GPL17021
Series:
GSE75370 GSE75632
Download data: CSV
Sample
Accession:
GSM1954033
ID:
301954033
11.

Myf5_ChIP_Rep1_Rep2

Organism:
Mus musculus
Source name:
ChIP-Seq with Myf5 antibody Sc-302x (lot CO612) in mouse M&M MEF cells transduced with Myf5
Platform:
GPL17021
Series:
GSE75370 GSE75632
Download data: CSV
Sample
Accession:
GSM1954032
ID:
301954032
12.

MyoD_ChIP_Rep1_Rep2

Organism:
Mus musculus
Source name:
ChIP-Seq with MyoD antibody 6975 in mouse M&M MEF cells transduced with MyoD
Platform:
GPL17021
Series:
GSE75370 GSE75632
Download data: CSV
Sample
Accession:
GSM1954031
ID:
301954031
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Supplemental Content

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