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Items: 6

1.

Tumor suppressor role of Ezh2 in an NRASQ61K driven model of Early T-cell Precursor Acute Lymphoblastic Leukemia (ChIP-Seq)

(Submitter supplied) Purpose: To characterize changes in genome-wide H3K27me3 associated with homozygous inactivation the Polycomb Repressive Complex 2 (PRC2) lysine methyltransferase Ezh2 in a mouse model of earlt T-cell precursor ALL (ETP-ALL) Methods: We performed Chip-seq for the H3K27me3 Chromatin mark on Ezh2ff and Ezh2ko cells NRASQ61K leukemias. Results: Inactivation of Ezh2 in this model leads to accelerated leukemia development. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL13112
4 Samples
Download data: BW, TXT
Series
Accession:
GSE76601
ID:
200076601

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 2000 (Mus musculus)

Organism:
Mus musculus
8348 Series
188708 Samples
Download data
Platform
Accession:
GPL13112
ID:
100013112

3.

Ezh2ko H3K27me3 ChIP

Organism:
Mus musculus
Source name:
Bone marrow
Platform:
GPL13112
Series:
GSE76601 GSE76603
Download data: BW, TXT
Sample
Accession:
GSM2028878
ID:
302028878

SRA Run Selector

4.

Ezh2ff H3K27me3 ChIP

Organism:
Mus musculus
Source name:
Bone marrow
Platform:
GPL13112
Series:
GSE76601 GSE76603
Download data: BW, TXT
Sample
Accession:
GSM2028877
ID:
302028877

SRA Run Selector

5.

Ezh2ko input

Organism:
Mus musculus
Source name:
Bone marrow
Platform:
GPL13112
Series:
GSE76601 GSE76603
Download data
Sample
Accession:
GSM2028876
ID:
302028876

SRA Run Selector

6.

Ezh2ff input

Organism:
Mus musculus
Source name:
Bone marrow
Platform:
GPL13112
Series:
GSE76601 GSE76603
Download data
Sample
Accession:
GSM2028875
ID:
302028875

SRA Run Selector

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db=gds|term=GSE76601[Accession]|query=35|qty=2|blobid=MCID_6733e4153ec0a11b447e77b1|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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