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Items: 14

1.

A long noncoding RNA lincRNA-EPS acts as a transcriptional brake to restrain inflammation

(Submitter supplied) LincRNA-EPS is a long noncoding RNA that is expressed in macrophages and downregulated upon exposure to diverse microbial products. Analysis of macrophages from lincRNA-EPS-deficient mice revealed a specific role for this lincRNA in restraining immune response gene (IRG) expression. Mechanistically, lincRNA-EPS associates with chromatin at regulatory regions of IRGs to repress their transcription. To gain insight into the molecular function of lincRNA-EPS on chromatin, we generated ATAC-Seq libraries from wildtype and lincRNA-EPS-deficient macrophages stimulated with LPS.
Organism:
Mus musculus
Type:
Other
Platform:
GPL19057
12 Samples
Download data: NARROWPEAK
Series
Accession:
GSE78873
ID:
200078873

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina NextSeq 500 (Mus musculus)

Organism:
Mus musculus
9731 Series
284210 Samples
Download data
Platform
Accession:
GPL19057
ID:
100019057

3.

KO Macrophage 6HR Rep2

Organism:
Mus musculus
Source name:
LincRNA-EPS KO mouse bone marrow-derived macrophage
Platform:
GPL19057
Series:
GSE78873
Download data: NARROWPEAK
Sample
Accession:
GSM2080028
ID:
302080028

SRA Run Selector

4.

KO Macrophage 6HR Rep1

Organism:
Mus musculus
Source name:
LincRNA-EPS KO mouse bone marrow-derived macrophage
Platform:
GPL19057
Series:
GSE78873
Download data: NARROWPEAK
Sample
Accession:
GSM2080027
ID:
302080027

SRA Run Selector

5.

KO Macrophage 2HR Rep2

Organism:
Mus musculus
Source name:
LincRNA-EPS KO mouse bone marrow-derived macrophage
Platform:
GPL19057
Series:
GSE78873
Download data: NARROWPEAK
Sample
Accession:
GSM2080026
ID:
302080026

SRA Run Selector

6.

KO Macrophage 2HR Rep1

Organism:
Mus musculus
Source name:
LincRNA-EPS KO mouse bone marrow-derived macrophage
Platform:
GPL19057
Series:
GSE78873
Download data: NARROWPEAK
Sample
Accession:
GSM2080025
ID:
302080025

SRA Run Selector

7.

KO Macrophage 0HR Rep2

Organism:
Mus musculus
Source name:
LincRNA-EPS KO mouse bone marrow-derived macrophage
Platform:
GPL19057
Series:
GSE78873
Download data: NARROWPEAK
Sample
Accession:
GSM2080024
ID:
302080024

SRA Run Selector

8.

KO Macrophage 0HR Rep1

Organism:
Mus musculus
Source name:
LincRNA-EPS KO mouse bone marrow-derived macrophage
Platform:
GPL19057
Series:
GSE78873
Download data: NARROWPEAK
Sample
Accession:
GSM2080023
ID:
302080023

SRA Run Selector

9.

WT Macrophage 6HR Rep2

Organism:
Mus musculus
Source name:
WT mouse bone marrow-derived macrophage
Platform:
GPL19057
Series:
GSE78873
Download data: NARROWPEAK
Sample
Accession:
GSM2080022
ID:
302080022

SRA Run Selector

10.

WT Macrophage 6HR Rep1

Organism:
Mus musculus
Source name:
WT mouse bone marrow-derived macrophage
Platform:
GPL19057
Series:
GSE78873
Download data: NARROWPEAK
Sample
Accession:
GSM2080021
ID:
302080021

SRA Run Selector

11.

WT Macrophage 2HR Rep2

Organism:
Mus musculus
Source name:
WT mouse bone marrow-derived macrophage
Platform:
GPL19057
Series:
GSE78873
Download data: NARROWPEAK
Sample
Accession:
GSM2080020
ID:
302080020

SRA Run Selector

12.

WT Macrophage 2HR Rep1

Organism:
Mus musculus
Source name:
WT mouse bone marrow-derived macrophage
Platform:
GPL19057
Series:
GSE78873
Download data: NARROWPEAK
Sample
Accession:
GSM2080019
ID:
302080019

SRA Run Selector

13.

WT Macrophage 0HR Rep2

Organism:
Mus musculus
Source name:
WT mouse bone marrow-derived macrophage
Platform:
GPL19057
Series:
GSE78873
Download data: NARROWPEAK
Sample
Accession:
GSM2080018
ID:
302080018

SRA Run Selector

14.

WT Macrophage 0HR Rep1

Organism:
Mus musculus
Source name:
WT mouse bone marrow-derived macrophage
Platform:
GPL19057
Series:
GSE78873
Download data: NARROWPEAK
Sample
Accession:
GSM2080017
ID:
302080017

SRA Run Selector

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