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Items: 8

1.

Integrated Systems Biology Analysis of KSHV Latent Infection Reveals Viral Induction and Reliance on Peroxisome Mediated Lipid Metabolism

(Submitter supplied) Kaposi’s Sarcoma herpesvirus (KSHV), an oncogenic virus, modulates host cell signaling and metabolism to maintain latent infection. To unravel the underlying cellular mechanisms modulated by KSHV, we identified changes in the host proteome, phosphoproteome and transcriptome landscape upon KSHV infection of endothelial cells. A Steiner Forest algorithm was used to integrate proteomic, phosphoproteomic and transcriptomic data with transcriptome based predicted transcription factor activity to identify cellular networks altered by latent KSHV.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
6 Samples
Download data: TXT
2.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
3.

TIME_KSHV_3

Organism:
Homo sapiens
Source name:
dermal microvasculature
Platform:
GPL16791
Series:
GSE84237
Download data
Sample
Accession:
GSM2229995
ID:
302229995
4.

TIME_KSHV_2

Organism:
Homo sapiens
Source name:
dermal microvasculature
Platform:
GPL16791
Series:
GSE84237
Download data
Sample
Accession:
GSM2229994
ID:
302229994
5.

TIME_KSHV_1

Organism:
Homo sapiens
Source name:
dermal microvasculature
Platform:
GPL16791
Series:
GSE84237
Download data
Sample
Accession:
GSM2229993
ID:
302229993
6.

TIME_Mock_3

Organism:
Homo sapiens
Source name:
dermal microvasculature
Platform:
GPL16791
Series:
GSE84237
Download data
Sample
Accession:
GSM2229992
ID:
302229992
7.

TIME_Mock_2

Organism:
Homo sapiens
Source name:
dermal microvasculature
Platform:
GPL16791
Series:
GSE84237
Download data
Sample
Accession:
GSM2229991
ID:
302229991
8.

TIME_Mock_1

Organism:
Homo sapiens
Source name:
dermal microvasculature
Platform:
GPL16791
Series:
GSE84237
Download data
Sample
Accession:
GSM2229990
ID:
302229990
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Supplemental Content

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