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Items: 1 to 20 of 39

1.

Gene expression profiling in three primary human cell lines treated with atorvastatin or an inhibitor of Rho kinase

(Submitter supplied) Inhibitors of Rho kinase (ROCK) are a new class of drugs with potential benefit in oncology, neurology, and fibrotic and cardiovascular diseases. ROCK inhibitors modulate many cellular functions, some of which are similar to the pleiotropic (non-lipid lowering) effects of statins, suggesting additive or synergistic properties. Studies to date have used compounds which inhibit both isoforms of ROCK, ROCK1 and ROCK2. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS2987
Platform:
GPL2507
36 Samples
Download data: TXT
Series
Accession:
GSE8686
ID:
200008686

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.
Full record GDS2987

Comparison of Rho kinase inhibitor and atorvastatin effects on primary cell lines

Analysis of three primary cell lines treated with Rho kinase (ROCK) 2 inhibitor SLx-2119 or with atorvastatin. Effects of ROCK inhibitors overlap to some extent with the pleiotropic (nonlipid lowering) effects of statins. Results suggest possible synergistic effects between the two classes of drugs.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 4 agent, 3 cell line sets
Platform:
GPL2507
Series:
GSE8686
36 Samples
Download data: TXT
DataSet
Accession:
GDS2987
ID:
2987

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

3.

Sentrix Human-6 Expression BeadChip

(Submitter supplied) The Sentrix Human-6 BeadChip can be used to study expression of over 47,000 human transcripts. Researchers can generate whole-genome expression profiles for 6 samples in parallel on a single BeadChip. Array is composed of 3 micron features with average feature redundancy of 30-fold . All features are QCed by sequential hybridizations process called array decoding. Probes are fully screened all-full-length 50-mers. more...
Organism:
Homo sapiens
7 DataSets
55 Series
1420 Samples
Download data: CSV
Platform
Accession:
GPL2507
ID:
100002507

4.

HMVEC_atorvastatin_rep2

Organism:
Homo sapiens
Source name:
Human Microvascular Endothelial Cells, atorvastatin treated 24 h
Platform:
GPL2507
Series:
GSE8686
Dataset:
GDS2987
Download data: TXT
Sample
Accession:
GSM215344
ID:
300215344

5.

Fibroblasts_SLx2119_rep3

Organism:
Homo sapiens
Source name:
Normal Human Dermal Fibroblasts, SLx-2119 treated 24 h
Platform:
GPL2507
Series:
GSE8686
Dataset:
GDS2987
Download data: TXT
Sample
Accession:
GSM215341
ID:
300215341

6.

Fibroblasts_SLx2119_rep2

Organism:
Homo sapiens
Source name:
Normal Human Dermal Fibroblasts, SLx-2119 treated 24 h
Platform:
GPL2507
Series:
GSE8686
Dataset:
GDS2987
Download data: TXT
Sample
Accession:
GSM215340
ID:
300215340

7.

Fibroblasts_SLx2119_rep1

Organism:
Homo sapiens
Source name:
Normal Human Dermal Fibroblasts, SLx-2119 treated 24 h
Platform:
GPL2507
Series:
GSE8686
Dataset:
GDS2987
Download data: TXT
Sample
Accession:
GSM215339
ID:
300215339

8.

Fibroblasts_atorvastatin_mevalonate_rep3

Organism:
Homo sapiens
Source name:
Normal Human Dermal Fibroblasts, atorvastatin and mevalonate treated 24 h
Platform:
GPL2507
Series:
GSE8686
Dataset:
GDS2987
Download data: TXT
Sample
Accession:
GSM215338
ID:
300215338

9.

Fibroblasts_atorvastatin_mevalonate_rep2

Organism:
Homo sapiens
Source name:
Normal Human Dermal Fibroblasts, atorvastatin and mevalonate treated 24 h
Platform:
GPL2507
Series:
GSE8686
Dataset:
GDS2987
Download data: TXT
Sample
Accession:
GSM215337
ID:
300215337

10.

Fibroblasts_atorvastatin_mevalonate_rep1

Organism:
Homo sapiens
Source name:
Normal Human Dermal Fibroblasts, atorvastatin and mevalonate treated 24 h
Platform:
GPL2507
Series:
GSE8686
Dataset:
GDS2987
Download data: TXT
Sample
Accession:
GSM215336
ID:
300215336

11.

Fibroblasts_atorvastatin_rep3

Organism:
Homo sapiens
Source name:
Normal Human Dermal Fibroblasts, atorvastatin treated 24 h
Platform:
GPL2507
Series:
GSE8686
Dataset:
GDS2987
Download data: TXT
Sample
Accession:
GSM215335
ID:
300215335

12.

Fibroblasts_atorvastatin_rep2

Organism:
Homo sapiens
Source name:
Normal Human Dermal Fibroblasts, atorvastatin treated 24 h
Platform:
GPL2507
Series:
GSE8686
Dataset:
GDS2987
Download data: TXT
Sample
Accession:
GSM215334
ID:
300215334

13.

Fibroblasts_atorvastatin_rep1

Organism:
Homo sapiens
Source name:
Normal Human Dermal Fibroblasts, atorvastatin treated 24 h
Platform:
GPL2507
Series:
GSE8686
Dataset:
GDS2987
Download data: TXT
Sample
Accession:
GSM215333
ID:
300215333

14.

Fibroblasts_vehicle_rep3

Organism:
Homo sapiens
Source name:
Normal Human Dermal Fibroblasts, vehicle treated 24 h
Platform:
GPL2507
Series:
GSE8686
Dataset:
GDS2987
Download data: TXT
Sample
Accession:
GSM215332
ID:
300215332

15.

Fibroblasts_vehicle_rep2

Organism:
Homo sapiens
Source name:
Normal Human Dermal Fibroblasts, vehicle treated 24 h
Platform:
GPL2507
Series:
GSE8686
Dataset:
GDS2987
Download data: TXT
Sample
Accession:
GSM215331
ID:
300215331

16.

Fibroblasts_vehicle_rep1

Organism:
Homo sapiens
Source name:
Normal Human Dermal Fibroblasts, vehicle treated 24 h
Platform:
GPL2507
Series:
GSE8686
Dataset:
GDS2987
Download data: TXT
Sample
Accession:
GSM215330
ID:
300215330

17.

PASMC_SLx2119_rep3

Organism:
Homo sapiens
Source name:
Human Pulmonary Artery Smooth Muscle Cells, SLx-2119 treated 24 h
Platform:
GPL2507
Series:
GSE8686
Dataset:
GDS2987
Download data: TXT
Sample
Accession:
GSM215329
ID:
300215329

18.

PASMC_SLx2119_rep2

Organism:
Homo sapiens
Source name:
Human Pulmonary Artery Smooth Muscle Cells, SLx-2119 treated 24 h
Platform:
GPL2507
Series:
GSE8686
Dataset:
GDS2987
Download data: TXT
Sample
Accession:
GSM215328
ID:
300215328

19.

PASMC_SLx2119_rep1

Organism:
Homo sapiens
Source name:
Human Pulmonary Artery Smooth Muscle Cells, SLx-2119 treated 24 h
Platform:
GPL2507
Series:
GSE8686
Dataset:
GDS2987
Download data: TXT
Sample
Accession:
GSM215327
ID:
300215327

20.

PASMC_atorvastatin_mevalonate_rep3

Organism:
Homo sapiens
Source name:
Human Pulmonary Artery Smooth Muscle Cells, atorvastatin and mevalonate treated 24 h
Platform:
GPL2507
Series:
GSE8686
Dataset:
GDS2987
Download data: TXT
Sample
Accession:
GSM215326
ID:
300215326

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