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Items: 4

1.

DNA methylation changes are a late event in Acute Promyelocytic Leukemia and coincide with loss of transcription factor binding

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Methylation profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by genome tiling array
4 related Platforms
61 Samples
Download data: TXT
Series
Accession:
GSE42119
ID:
200042119
2.

DNA methylation changes are a late event in Acute Promyelocytic Leukemia and coincide with loss of transcription factor binding (sequencing)

(Submitter supplied) The origin of aberrant DNA methylation in cancer remains largely unknown. In this study, we elucidated the DNA methylome in primary Acute Promyelocytic Leukemia (APL) and the role of PML-RARa in establishing these patterns. APL patients showed increased genome-wide DNA methylation with higher variability than healthy CD34+ cells, promyelocytes and remission bone marrow. A core set of differentially methylated regions in APL was identified. more...
Organism:
Mus musculus; Homo sapiens
Type:
Methylation profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL15456 GPL11154 GPL16173
51 Samples
Download data: TXT
Series
Accession:
GSE42044
ID:
200042044
3.

Illumina HiScanSQ (Homo sapiens)

Platform
Accession:
GPL15456
ID:
100015456
4.

RRBS remission bone marrow APL_10325

Organism:
Homo sapiens
Source name:
Density centrifuged bone marrow
Platform:
GPL15456
Series:
GSE42044 GSE42119
Download data: TXT
Sample
Accession:
GSM1031224
ID:
301031224
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