GSM1044743[Accession] - GEO DataSets - NCBI

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Items: 3

Select item 2000425431.

Loss of imprinting at the CTCF binding sites in the DLK1-DIO3 domain reactivates microRNA expression in acute promyelocytic leukaemia

(Submitter supplied) We report the DNA-methylation profiling of 10 regions selected from the DLK1-DIO3 domain on chromosome 14q32 in BM/PB samples from patients with acute promyelocytic leukaemia (APL), other subclasses of acute myeloid leukaemia and healthy donors, using high-throughput amplicon bisulfite sequencing with Roche 454 technology. We identify monoallelic-hypermethylation in APL only at the differentially methylated region (DMR) located upstream from the MEG3 gene (MEG3-DMR), whereas no changes in the DNA methylation profile were detected at the imprinting control region of the domain (IG-DMR) among the samples analysed. more...

Organism:: Homo sapiens

Type:: Methylation profiling by high throughput sequencing

Platform:: GPL14603
47 Samples

Download data: TXT, WIG

Series

Accession:: GSE42543

ID:: 200042543

PubMed Similar studies SRA Run Selector

Select item 1000146032.

454 GS FLX Titanium (Homo sapiens)

Organism:: Homo sapiens

13 Series
146 Samples

Platform

Accession:: GPL14603

ID:: 100014603

Select item 3010447433.

Organism:: Homo sapiens

Source name:: Bone Marrow Mononuclear Cells

Platform:: GPL14603
Series:: GSE42543

Download data: WIG

Sample

Accession:: GSM1044743

ID:: 301044743

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GSM1044743[Accession] (3)
GEO DataSets
uveal autoantigen with coiled-coil domains and ankyrin repeats isoform X4 [Homo ...
uveal autoantigen with coiled-coil domains and ankyrin repeats isoform X4 [Homo sapiens]
gi|2462544954|ref|XP_054234329.1|

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