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Items: 4

1.

Examination of genome-wide methylation changes in lung cancer cell lines A549 (A) and HTB56 (H) [RRBS-Seq experiments]

(Submitter supplied) Cancer cell phenotypes are partially determined by epigenetic specifications such as DNA methylation. Metastasis development is a late event in cancerogenesis and might be associated with epigenetic alterations. Here, we analyzed genome wide DNA methylation changes that were associated with pro-metastatic phenotypes in non-small cell lung cancer with Reduced Representation Bisulfite Sequencing. DNMT-inhibition by 5-Azacytidine at low concentrations reverted the pro-metastatic phenotype. more...
Organism:
Homo sapiens
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL15456
17 Samples
Download data: TXT
Series
Accession:
GSE52140
ID:
200052140

PubMed Similar studies SRA Run Selector

2.

DNA Methyltransferase inhibition reverses epigenetically embedded phenotypes in lung cancer preferentially affecting Polycomb target genes

(Submitter supplied) Cancer cell phenotypes are partially determined by epigenetic specifications such as DNA methylation. Metastasis development is a late event in cancerogenesis and might be associated with epigenetic alterations. Here, we analyzed genome wide DNA methylation changes that were associated with pro-metastatic phenotypes in non-small cell lung cancer with Reduced Representation Bisulfite Sequencing. DNMT-inhibition by 5-Azacytidine at low concentrations reverted the pro-metastatic phenotype. more...
Organism:
Homo sapiens
Type:
Expression profiling by array; Methylation profiling by array; Methylation profiling by high throughput sequencing
Platforms:
GPL6244 GPL15456 GPL8490
37 Samples
Download data: CEL, TXT
Series
Accession:
GSE44390
ID:
200044390

PubMed Similar studies Analyze with GEO2R

3.

Illumina HiScanSQ (Homo sapiens)

Organism:
Homo sapiens
122 Series
2006 Samples
Download data
Platform
Accession:
GPL15456
ID:
100015456

4.

A3R_d13_1000

Organism:
Homo sapiens
Source name:
RRBS highly metastatic A549 cell line at day 13 after 6 days 5-Azacytidine treatment at 1000 nM and 7 days release in normal media.
Platform:
GPL15456
Series:
GSE44390 GSE52140
Download data: TXT
Sample
Accession:
GSM1084243
ID:
301084243

SRA Run Selector

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db=gds|term=GSM1084243[Accession]|query=4|qty=2|blobid=MCID_673b92ada56b24050d34591f|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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