GSM1094809[Accession] - GEO DataSets

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Items: 3

Select item 2000449701.

Genome-wide DNA methylation profiles of human hepatocellular carcinoma

(Submitter supplied) Introduction: Hepatocellular carcinoma (HCC) is one of the most aggressive solid tumors and oncogenic pathways (e.g Akt, IGF signaling) are often activated in high proliferating HCC. Among several genetic alterations, epigenetic changes seem to be involved in the development and progression of HCC. DNA hypermethylation of promoter regions is almost always associated with transcriptional silencing and can lead to inactivation of tumor suppressor genes (TSG) in cancer cells. more...

Organism:: Homo sapiens

Type:: Methylation profiling by array

Platform:: GPL8490
102 Samples

Download data: TXT

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Accession:: GSE44970

ID:: 200044970

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000084902.

Illumina HumanMethylation27 BeadChip (HumanMethylation27_270596_v.1.2)

(Submitter supplied) HumanMethylation27 DNA Analysis BeadChip allows researchers to interrogate 27,578 highly informative CpG sites per sample at single-nucleotide resolution. This 12-sample BeadChip features content derived from the well-annotated NCBI CCDS database (Genome Build 36) and is supplemented with more than 1,000 cancer-related genes described in published literature. Probe content has been enriched to deeply cover more than 150 well-established cancer genes known to show differential methylation patterns. more...