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Items: 4

1.

thrombopoietin-induced megakaryocyte differentiation with and without nicotinamide

(Submitter supplied) Culture of hematopoietic stem and progenitor cells in the presence of thrombopoietin induces megakaryocytic differentiation. Addition of nicotinamide to thrombopoietin-stimulated cultures results in significant increases in megkaryocytic differentiation including greater polyploidization and enhanced proplatelet formation. This study focuses on understanding the differences in the temporal gene expression pattern during differentiation with and without nicotinamide. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS2513
Platform:
GPL887
28 Samples
Download data
Series
Accession:
GSE4974
ID:
200004974
2.
Full record GDS2513

Nicotinamide effect on thrombopoietin-induced megakaryocyte differentiation in vitro

Analysis of thrombopoietin-cultured CD34+ cells at various time points up to 5 days following treatment with nicotinamide. Thrombopoietin induces CD34+ cells to differentiate into megakaryocytes. Results provide insight into the effect of nicotinamide on megakaryocyte differentiation.
Organism:
Homo sapiens
Type:
Expression profiling by array, log e ratio, 3 agent, 2 individual, 4 time sets
Platform:
GPL887
Series:
GSE4974
28 Samples
Download data
DataSet
Accession:
GDS2513
ID:
2513
3.

Agilent-012097 Human 1A Microarray (V2) G4110B (Feature Number version)

(Submitter supplied) Agilent's Human 1A Oligo Microarray (V2) includes over 20K 60-mer oligonucleotide probes, sourced from the Incyte Foundation Database, RefSeq, and GenBank, and are designed to span conserved exons across the transcripts of the targeted full length genes. Coupled with Agilent's probe selection and validation processes, this design method gives the customer maximum confidence in data quality and prevents redundancy in gene coverage. more...
Organism:
Homo sapiens
8 DataSets
98 Series
1 Related Platform
2172 Samples
Download data: TXT
Platform
Accession:
GPL887
ID:
100000887
4.

Donor MK09 thrombopoietin + nicotinamide Day 10 rep2

Organism:
Homo sapiens
Source name:
Donor MK09 thrombopoietin + nicotinamide Day 10 (channel 1) Universal Reference RNA (channel 2)
Platform:
GPL887
Series:
GSE4974
Dataset:
GDS2513
Download data
Sample
Accession:
GSM112284
ID:
300112284
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