GSM1129338[Accession] - GEO DataSets - NCBI

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Items: 3

Select item 2000459821.

EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation

(Submitter supplied) The EZH2 histone methyltransferase is highly expressed in germinal center (GC) B-cells and targeted by somatic mutations in B-cell lymphomas. Here we find that EZH2 deletion or pharmacologic inhibition suppresses GC formation and functions in mice. EZH2 represses proliferation checkpoint genes and helps establish bivalent chromatin domains at key regulatory loci to transiently suppress GC B-cell differentiation. more...

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL13112 GPL11154 GPL10999
61 Samples

Download data: BED, TXT, WIG

Series

Accession:: GSE45982

ID:: 200045982

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 1000131122.

Illumina HiSeq 2000 (Mus musculus)

Organism:: Mus musculus

8343 Series
188684 Samples

Platform

Accession:: GPL13112

ID:: 100013112

Select item 3011293383.

BCL1 Y641N GSK343

Organism:: Mus musculus

Source name:: BCL1 cell line transduced with Y641N EZH2

Platform:: GPL13112
Series:: GSE45982

Download data: TXT

Sample

Accession:: GSM1129338

ID:: 301129338

SRA Run Selector

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GSM1129338[Accession] (3)
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UNVERIFIED: Phyllostomus hastatus long-wavelength sensitive opsin-like (OPN1LW) ...
UNVERIFIED: Phyllostomus hastatus long-wavelength sensitive opsin-like (OPN1LW) gene, partial sequence
gi|1483540792|gb|MH179239.1|

Nucleotide
unnamed protein product [Homo sapiens]
unnamed protein product [Homo sapiens]
gi|189054420|dbj|BAG37193.1|

Protein

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