GSM1249166[Accession] - GEO DataSets

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Items: 4

Select item 2000516121.

Transcriptome profiling in Engrailed2 knockout mice reveals common molecular pathways associated with ASD.

(Submitter supplied) Background: Transcriptome analysis has been used in autism spectrum disorder (ASD) to unravel common pathogenic pathways based on the assumption that distinct rare genetic variants or epigenetic modifications affect common biological pathways dysregulated in ASD. To unravel recurrent ASD-related neuropathological mechanisms, we took advantage of the En2-/- mouse model and performed transcriptome profiling on cerebellar and hippocampal adult tissues. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Datasets:: GDS5241 GDS6016
Platform:: GPL7202
12 Samples

Download data: TXT

Series

Accession:: GSE51612

ID:: 200051612

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 60162.

Transcription factor engrailed-2 loss-of-function model of autism spectrum disorder: hippocampus

Analysis of hippocampal samples from engrailed-2 (En2) mutant adults. The En2-/- animals are a model for autism spectrum disorder (ASD). The hippocampus is a brain area profoundly affected in ASD patients. Results provide insight into molecular mechanisms underlying ASD-related neuropathology.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 genotype/variation sets

Platform:: GPL7202
Series:: GSE51612
6 Samples

Download data: TXT

DataSet

Accession:: GDS6016

ID:: 6016

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000072023.

Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version)

(Submitter supplied) Designed to truly represent all known genes in the mouse genome and their resulting transcripts, Agilent's Whole Mouse Genome Oligo – 4X44K microarray is comprised of 41,534 60-mer oligonucleotide probes representing over 41,000 mouse genes and transcripts. Content for this microarray was generated from leading public databases, including RefSeq, RIKEN, NIA, Ensembl, RIKEN, UCSC Goldenpath, and Unigene. more...