GEO DataSets

(Submitter supplied) U4/U6 di-snRNPs were disrupted and singular U4 and U6 snRNPs accumulated in egy mutant embryos, establishing the recycling function of p110 in vivo. Based on microarray analyses, a subset of spliceosome components and splicing-related factors was coordinately upregulated in the egy mutant. This revealed an extensive network of coregulated components of the spliceosome cycle, compensating – albeit inefficiently – for the recycling defect. more...

Organism:

Danio rerio

Type:

Expression profiling by array

Dataset:

GDS2550

Platform:

GPL1319

10 Samples

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Analysis of 3 and 5-day egy mutant embryos, which contain a mutation in recycling factor p110. This mutation leads to microcephaly and thymus hypoplasia. U4/U6 snRNPs are disrupted in egy mutants. Results provide insight into the mechanisms underlying these developmental defects.

Organism:

Danio rerio

Type:

Expression profiling by array, count, 2 age, 2 genotype/variation sets

Platform:

GPL1319

Series:

GSE5586

10 Samples

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(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html The Affymetrix GeneChip Zebrafish Genome Array can be used to study gene expression of over 14,900 Danio rerio transcripts. Sequence information for this array was selected from the following public data sources: RefSeq (July 2003), GenBank (release 136.0, June 2003), dbEST (July 2003), and UniGene (Build 54, June 2003). more...

Organism:

Danio rerio

18 DataSets

135 Series

1 Related Platform

1713 Samples

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