GSM1328982[Accession] - GEO DataSets

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Items: 4

Select item 2000550641.

Therapeutic Targeting of BET Bromodomain Proteins in Castration-Resistant Prostate Cancer

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL15433 GPL4133
83 Samples

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Series

Accession:: GSE55064

ID:: 200055064

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000550622.

Therapeutic Targeting of BET Bromodomain Proteins in Castration-Resistant Prostate Cancer (ChIP-Seq)

(Submitter supplied) Men who develop metastatic castration-resistant prostate cancer (CRPC) invariably succumb to the disease. The development and progression to CRPC following androgen ablation therapy is predominantly driven by unregulated androgen receptor (AR) signaling1-3. Despite the success of recently approved therapies targeting AR signaling such as abiraterone4-6 and second generation anti-androgens MDV3100 (enzalutamide)7,8, durable responses are limited, presumably due to acquired resistance. more...