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Items: 4

1.

Therapeutic Targeting of BET Bromodomain Proteins in Castration-Resistant Prostate Cancer

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL15433 GPL4133
83 Samples
Download data: BW, TXT
Series
Accession:
GSE55064
ID:
200055064
2.

Therapeutic Targeting of BET Bromodomain Proteins in Castration-Resistant Prostate Cancer (microarray)

(Submitter supplied) Men who develop metastatic castration-resistant prostate cancer (CRPC) invariably succumb to the disease. The development and progression to CRPC following androgen ablation therapy is predominantly driven by unregulated androgen receptor (AR) signaling1-3. Despite the success of recently approved therapies targeting AR signaling such as abiraterone4-6 and second generation anti-androgens MDV3100 (enzalutamide)7,8, durable responses are limited, presumably due to acquired resistance. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL4133
48 Samples
Download data: TXT
Series
Accession:
GSE55063
ID:
200055063
3.

Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)

(Submitter supplied) This multi-pack (4X44K) formatted microarray represents a compiled view of the human genome as it is understood today. The sequence information used to design this product was derived from a broad survey of well known sources such as RefSeq, Goldenpath, Ensembl, Unigene and others. The resulting view of the human genome covers 41K unique genes and transcripts which have been verified and optimized by alignment to the human genome assembly and by Agilent's Empirical Validation process. more...
Organism:
Homo sapiens
10 DataSets
838 Series
3 Related Platforms
15421 Samples
Download data: TXT
Platform
Accession:
GPL4133
ID:
100004133
4.

DU145 cells treated with JQ1 Replicate 2 DU145_JQ1_0.5µM_rep2

Organism:
Homo sapiens
Source name:
Total RNA from DU145 cells treated with JQ1 (channel 1) Total RNA from DU145 cells treated with DMSO (channel 2)
Platform:
GPL4133
Series:
GSE55063 GSE55064
Download data: TXT
Sample
Accession:
GSM1328991
ID:
301328991
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